Polanczyk Andrzej, Piechota-Polanczyk Aleksandra, Stefańczyk Ludomir, Strzelecki Michał
The Main School of Fire Service, 01-629 Warsaw, Poland.
Department of Medical Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.
Diagnostics (Basel). 2020 Sep 23;10(10):737. doi: 10.3390/diagnostics10100737.
The aim of this study was to prepare a self-made mathematical algorithm for the estimation of risk of stent-graft migration with the use of data on abdominal aortic aneurysm (AAA) size and geometry of blood flow through aneurysm sac before or after stent-graft implantation. AngioCT data from 20 patients aged 50-60 years, before and after stent-graft placement in the AAA was analyzed. In order to estimate the risk of stent-graft migration for each patient we prepared an opposite spatial configuration of virtually reconstructed stent-graft with long body or short body. Thus, three groups of 3D geometries were analyzed: 20 geometries representing 3D models of aneurysm, 20 geometries representing 3D models of long body stent-grafts, and 20 geometries representing 3D models of short body stent-graft. The proposed self-made algorithm demonstrated its efficiency and usefulness in estimating wall shear stress (WSS) values. Comparison of the long or short type of stent-graft with AAA geometries allowed to analyze the implants' spatial configuration. Our study indicated that short stent-graft, after placement in the AAA sac, generated lower drug forces compare to the long stent-graft. Each time shape factor was higher for short stent-graft compare to long stent-graft.
本研究的目的是利用腹主动脉瘤(AAA)大小以及支架植入前后通过瘤腔的血流几何形状数据,制备一种自制的数学算法,用于估计支架移植物迁移风险。分析了20例年龄在50 - 60岁患者在AAA内植入支架前后的血管CT数据。为了估计每位患者支架移植物迁移的风险,我们制备了具有长主体或短主体的虚拟重建支架移植物的相反空间配置。因此,分析了三组三维几何形状:20种代表动脉瘤三维模型的几何形状、20种代表长主体支架移植物三维模型的几何形状以及20种代表短主体支架移植物三维模型的几何形状。所提出的自制算法在估计壁面剪应力(WSS)值方面显示出其有效性和实用性。将长型或短型支架移植物与AAA几何形状进行比较,可以分析植入物的空间配置。我们的研究表明,与长支架移植物相比,短支架移植物植入AAA瘤腔后产生的作用力较小。每次短支架移植物的形状因子都比长支架移植物高。