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斜坡病变:MRI诊断准确性与治疗疗效的系统评价

Ramp lesions: a systematic review of MRI diagnostic accuracy and treatment efficacy.

作者信息

Moreira José, Almeida Margarida, Lunet Nuno, Gutierres Manuel

机构信息

Faculty of Medicine, University of Porto, Alameda Hernâni Monteiro, 4200-319, Porto, Portugal.

EPIUnit-Instituto de Saúde Pública, University of Porto, Porto, Portugal.

出版信息

J Exp Orthop. 2020 Sep 25;7(1):71. doi: 10.1186/s40634-020-00287-x.

Abstract

PURPOSE

We conducted a systematic review of the published literature to assess the accuracy of Magnetic Resonance Imaging (MRI) in establishing the presence of ramp lesions (RLs) in Anterior Cruciate Ligament (ACL) deficient knees and the clinical efficacy of the surgical repair of RLs.

METHODS

A comprehensive search of the MEDLINE, Web of Science and Scopus databases was performed according to PRISMA guidelines. Studies assessing MRI diagnostic accuracy for RLs or the clinical effect of RL repair in participants with ACL injuries were included. Diagnostic accuracy measures were pooled and plotted in forest plots. Preoperative and at last follow-up treatment efficacy outcome measures were extracted and plotted in forest plots, for graphical comprehension.

RESULTS

Sixteen studies met the criteria and were included. The diagnostic analysis showed a pooled sensitivity, specificity, positive and negative likelihood ratios of 65.1% (95% CI, 59.73 to 70.42), 91.6% (95% CI, 89.14 to 94.05), 2.91 (95% CI, 2.38-3.55) and 0.53 (95% CI, 0.44-0.64), respectively, with high heterogeneity (I above 80%) for all measures. Treatment analysis showed improved Lysholm Knee Score, IKDC score and laxity difference between the knees in all studies after meniscal suture repair. A separate analysis showed no differences between repair of smaller, stable, RLs with meniscal sutures and repair with abrasion and trephination only.

CONCLUSION

Although the results present considerable heterogeneity, MRI seems to demonstrate moderate accuracy in the diagnosis of RLs in patients with ACL tear and the surgical repair of RLs can be associated with improved overall outcomes.

摘要

目的

我们对已发表的文献进行了系统评价,以评估磁共振成像(MRI)在确定前交叉韧带(ACL)损伤膝关节中斜行损伤(RLs)存在方面的准确性以及RLs手术修复的临床疗效。

方法

根据PRISMA指南对MEDLINE、科学网和Scopus数据库进行了全面检索。纳入评估RLs的MRI诊断准确性或ACL损伤参与者中RL修复的临床效果的研究。汇总诊断准确性指标并绘制森林图。提取术前和最后随访时的治疗效果指标并绘制森林图,以便直观理解。

结果

16项研究符合标准并被纳入。诊断分析显示,合并敏感度、特异度、阳性似然比和阴性似然比分别为65.1%(95%CI,59.73至70.42)、91.6%(95%CI,89.14至94.05)、2.91(95%CI,2.38 - 3.55)和0.53(95%CI,0.44 - 0.64),所有指标均具有高度异质性(I大于80%)。治疗分析显示,在所有半月板缝合修复后的研究中,Lysholm膝关节评分、IKDC评分以及双膝之间的松弛度差异均有所改善。单独分析显示,小型、稳定的RLs采用半月板缝合修复与仅采用磨损和环钻修复之间没有差异。

结论

尽管结果存在相当大的异质性,但MRI在诊断ACL撕裂患者的RLs方面似乎具有中等准确性,并且RLs的手术修复可能与整体预后改善相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a12f/7519018/bea27125444e/40634_2020_287_Fig1_HTML.jpg

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