Dermatographism associated with ocrelizumab.

Dermatographism is a disorder of unknown etiology that results in inducible hives from environmental stimuli. Here we report the first known case of dermatographism associated with ocrelizumab in a patient with relapsing remitting multiple sclerosis. The patient presented with pruritic linear raised rash approximately two weeks after her first infusion with ocrelizumab and was later diagnosed with dermatographism. This case highlights a potential rare adverse reaction to ocrelizumab and may provide insight into the biological underpinnings of dermatographism.