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霉酚酸成功治疗HIV相关的狼疮样肾小球肾炎。

Successful treatment of HIV-associated lupus-like glomerulonephritis with mycophenolic acid.

作者信息

Tiong Mark, Wilson Scott, Pham Alan, Chrysostomou Anastasia

机构信息

Department of Renal Medicine Alfred Health Melbourne Vic. Australia.

Department of Nephrology The Royal Melbourne Hospital Parkville Vic. Australia.

出版信息

Clin Case Rep. 2020 May 19;8(9):1601-1604. doi: 10.1002/ccr3.2955. eCollection 2020 Sep.

DOI:10.1002/ccr3.2955
PMID:32983458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7495868/
Abstract

HIV-associated lupus-like glomerulonephritis is an uncommon but well-described entity. Treatment has traditionally focused on control of HIV viremia with some using adjuvant steroids. Mycophenolic acid may prove to be a novel, nonsteroid, therapy in patients with active glomerulonephritis despite control of the underlying infection.

摘要

人类免疫缺陷病毒(HIV)相关的狼疮样肾小球肾炎是一种罕见但已有充分描述的病症。传统治疗主要集中于控制HIV病毒血症,一些人会使用辅助性类固醇。对于尽管潜在感染已得到控制但仍患有活动性肾小球肾炎的患者,霉酚酸可能被证明是一种新型的非类固醇疗法。

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Intern Med J. 2020 Feb;50(2):151-164. doi: 10.1111/imj.14414.
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增殖性狼疮性肾炎的免疫抑制治疗
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