Johnson Lynelle R, Vidal Sarah A, Brust Kelsey D, Keel M Kevin, Steffey Michele A
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA.
William R Pritchard Veterinary Medical Teaching Hospital, Davis, CA, USA.
JFMS Open Rep. 2020 Sep 15;6(2):2055116920957200. doi: 10.1177/2055116920957200. eCollection 2020 Jul-Dec.
An 8-year-old neutered male indoor cat was presented for evaluation of a year-long history of swelling over the bridge of the nose that extended from the subcutaneous tissue of the right upper eyelid to the dorsum of the skull. Intermittent regression of the mass lesion was reported with antibiotic or corticosteroid therapy; however, progressive swelling, malaise and hiding behavior persisted. CT revealed an aggressive osteolytic mass lesion in the right and left nasal cavities and extending into the frontal sinuses. Rhinoscopy using a 2.8 mm rigid telescope revealed somewhat normal-appearing turbinates rostrally and ventrally on the left side, with turbinate destruction on the right. After obtaining a biopsy from the right side of the nasal cavity, thick material filling the entire nasal cavity was visible caudally and was extracted endoscopically from a rostral approach. Surgical biopsy of the dorsal nasal bridge resulted in protrusion of inspissated material from the incision site. Rhinoscopic exploration revealed that the material extended into both frontal sinuses. Following extensive debridement and medical therapy, marked resolution of facial asymmetry was achieved.
Facial distortion is often considered suggestive of a neoplastic process; however, it can also be seen with fungal and mycobacterial infections, and, in this case, an inflammatory condition of unknown etiology. In this cat, aggressive intervention and debridement of necrotic debris resulted in substantial bony remodeling of the skull and return to normal activity levels.
一只8岁已绝育的室内雄性猫因鼻梁肿胀一年前来就诊,肿胀从右上眼睑皮下组织延伸至颅骨背侧。据报告,使用抗生素或皮质类固醇治疗后,肿块病变有间歇性消退;然而,肿胀仍在进展,猫出现不适和躲藏行为。CT显示左右鼻腔有侵袭性溶骨性肿块病变,并延伸至额窦。使用2.8毫米硬管望远镜进行鼻内镜检查发现,左侧鼻甲骨在鼻前端和腹侧外观基本正常,右侧鼻甲骨有破坏。从右侧鼻腔活检后,可见尾侧有填充整个鼻腔的浓稠物质,通过鼻前端入路经内镜取出。鼻梁背侧手术活检时,有浓缩物质从切口部位突出。鼻内镜探查发现该物质延伸至双侧额窦。经过广泛清创和药物治疗后,面部不对称明显改善。
面部畸形通常被认为提示肿瘤性病变;然而,在真菌感染和分枝杆菌感染以及本例病因不明的炎症性疾病中也可见到。在这只猫中,积极干预和清除坏死碎片导致颅骨大量骨质重塑,并恢复到正常活动水平。