Drinnon Kyle D, Sherali Samir, Cox Cameron T, MacKay Brendan J
Department of Orthopaedic Surgery, Texas Tech University Health Sciences Center, Lubbock, Tex.
University Medical Center, Lubbock, Tex.
Plast Reconstr Surg Glob Open. 2020 Aug 18;8(8):e3002. doi: 10.1097/GOX.0000000000003002. eCollection 2020 Aug.
Primary malignant tumors of the sternum are rare among bone tumors. Even with radical resection, the survival rate for sternal tumors remains low. Resection often results in significant bone defects in the chest wall, and reconstruction must provide adequate protection for pulmonary and respiratory structures. Flexible materials have historically been used for sternal reconstructions following failed sternotomies in cardiac surgery. Although these have had some success, they fail to provide adequate support for patients undergoing reconstruction secondary to tumor resection, who are otherwise healthy and active. Although rigid materials offer greater protection, they frequently cause chronic pain and respiratory complications. More recently, bone grafts have been used to reconstruct sternal defects, and the limited published reports are promising.
We present the case of a patient diagnosed with an extramedullary solitary bone plasmacytoma who underwent a sternal resection and reconstruction with an autogenous bone graft taken from the iliac crest and secured in place with 5 plates (3 sternal and 2 mandibular).
At 9-month follow-up, bone marrow biopsy showed no evidence of multiple myeloma. X-ray, computed tomography, and Pulmonary Function Test (PFT) scans confirmed graft stability, and the patient has returned to normal activities.
Sternal resection and reconstruction is an effective method for treating extramedullary solitary plasmacytoma when radiation is ineffective. In cases of significant segmental defects, iliac crest bone graft may be a viable option for repairing sternal defects following tumor resection.
原发性胸骨恶性肿瘤在骨肿瘤中较为罕见。即便进行根治性切除,胸骨肿瘤的生存率依然较低。切除手术常导致胸壁出现明显的骨缺损,而重建必须为肺部和呼吸结构提供充分保护。在心脏手术中,胸骨切开术失败后,柔性材料历来被用于胸骨重建。尽管这些材料取得了一些成功,但对于因肿瘤切除而进行重建的原本健康且活跃的患者而言,它们无法提供足够的支撑。虽然刚性材料能提供更好的保护,但它们常常引发慢性疼痛和呼吸并发症。最近,骨移植已被用于重建胸骨缺损,且有限的已发表报告显示前景良好。
我们报告一例被诊断为髓外孤立性骨浆细胞瘤的患者,该患者接受了胸骨切除,并使用取自髂嵴的自体骨移植进行重建,并用5块钢板(3块胸骨钢板和2块下颌骨钢板)固定到位。
在9个月的随访中,骨髓活检未显示多发性骨髓瘤的迹象。X线、计算机断层扫描和肺功能测试扫描证实了移植骨的稳定性,患者已恢复正常活动。
当放疗无效时,胸骨切除和重建是治疗髓外孤立性浆细胞瘤的有效方法。对于存在明显节段性缺损的病例,髂嵴骨移植可能是肿瘤切除后修复胸骨缺损的可行选择。