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[我院胎儿镜检查结果]

[Results of fetoscopic examinations at our hospital].

作者信息

Takayama M, Ogawa T, Yaguchi S, Fujiwara K, Funayama H, Soma H

出版信息

Nihon Sanka Fujinka Gakkai Zasshi. 1987 May;39(5):759-64.

PMID:3298469
Abstract

From 1983 to 1985, antenatal diagnosis by fetoscopy under ultrasound guidance has been performed at our institute for 17 pregnant women between 15 and 34 weeks of gestation. Indications for fetoscopy were visualization of the fetus, placenta, and amniotic membrane for morphological anomaly and fetal blood sampling for coagulation disorder. The diagnosis, made by visual observation of the fetus, blood coagulation tests, and karyotyping revealed 12 normal fetuses and 5 abnormal fetuses (one having chromosome abnormality, one amniotic band syndrome, one cephalothracopagus, one Beckwith-Wiedemann syndrome, and one sacral tumor). Courses of pregnancy following fetoscopy resulted in four normal full-term deliveries, six premature deliveries due to four hydramnions and two spontaneous ruptures of the membrane more than 14 weeks after fetoscopy. Three other pregnancies were interrupted due to intrauterine fetal death 11 weeks after fetoscopy in one case and to therapeutic abortion for maternal complications such as toxemia of pregnancy in two cases. The outcome of one case was unknown because the mother had moved away. The other pregnancy is still under observation at the third trimester. Although no complications in the fetuses were seen following fetoscopy, complications in the mothers included two cases of genital bleeding, one case of amniotic fluid leakage, and one cases of abruption of the fetal membrane. Symptoms in all four cases disappeared during several days of bed rest. These results demonstrate the importance of fetoscopy in prenatal diagnosis.

摘要

1983年至1985年期间,我院对17例妊娠15至34周的孕妇在超声引导下进行了胎儿镜产前诊断。胎儿镜检查的指征包括观察胎儿、胎盘和羊膜以发现形态异常,以及采集胎儿血液以检测凝血障碍。通过对胎儿的目视观察、凝血试验和染色体核型分析所做出的诊断显示,有12例胎儿正常,5例异常(1例染色体异常、1例羊膜带综合征、1例头部胸部联体双胎、1例贝克威思-维德曼综合征和1例骶骨肿瘤)。胎儿镜检查后的妊娠过程导致4例正常足月分娩,6例早产,其中4例因羊水过多,2例因胎儿镜检查后14周以上胎膜自然破裂。另外3例妊娠中,1例在胎儿镜检查后11周因宫内胎儿死亡而终止妊娠,2例因母亲出现如妊娠中毒等并发症而进行治疗性流产。1例的结局未知,因为母亲已搬走。另1例妊娠在孕晚期仍在观察中。尽管胎儿镜检查后未发现胎儿有并发症,但母亲的并发症包括2例生殖道出血、1例羊水渗漏和1例胎膜早剥。所有4例的症状在卧床休息数天后均消失。这些结果证明了胎儿镜检查在产前诊断中的重要性。

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