Physics Department, Pedagogical and Technological University of Colombia, Avenida Central del Norte 39-115, 150003 Tunja, Colombia.
Department of Nuclear Energy, Federal University of Pernambuco, Avenida Professor Luiz Freire 1000 CEP 50740-540, Recife, Pernambuco, Brazil.
Radiat Prot Dosimetry. 2020 Nov 6;191(1):1-8. doi: 10.1093/rpd/ncaa126.
The aim of this work was to estimate patient's organ absorbed doses from pediatric helical head computed tomography (CT) examinations using the Size-Specific Dose Estimate (SSDE) methodology and to determine organ dose to SSDE conversion coefficients for clinical routine. Patient-specific organ and tissue absorbed doses from 139 Head CT scans performed in pediatric patients from 0 to 15 years old in a Public Hospital in Tunja, Colombia were estimated. The calculations were made through Monte Carlo simulations, based on patient-specific information, dosimetric CT quantities (CTDIvol, DLP) and age-specific computational human phantoms matched to patients on the basis of gender and size. SSDE showed to be a good quantity for estimate patient-specific organ doses from pediatric head CT examinations when appropriate phantom's attenuation-based size metrics are chosen to match for any patient size. Strong correlations between absorbed dose and SSDE were found for skin (R2 = 0.99), brain (R2 = 0.98) and eyes (R2 = 0.97), respectively. Besides, a good correlation between SSDE and absorbed dose to the red bone marrow (tissue extended outside the scan coverage) was observed (R2 = 0.94). SSDE-to-organ-dose conversion coefficients obtained in this study provide a practical way to estimate patient-specific organ head CT doses.
本研究旨在使用体型特异性剂量估算值(Size-Specific Dose Estimate,SSDE)方法来估算儿科螺旋头部 CT(CT)检查中患者的器官吸收剂量,并确定临床常规中 SSDE 向器官剂量的转换系数。在哥伦比亚图尼加的一家公立医院中,对 0 至 15 岁的 139 名接受头部 CT 检查的儿科患者的特定器官和组织吸收剂量进行了估计。通过蒙特卡罗模拟进行计算,基于患者的具体信息、剂量学 CT 量(CTDIvol、DLP)以及与患者基于性别和体型匹配的年龄特异性计算人体模型。当选择适当的基于体模衰减的体型指标来匹配任何患者体型时,SSDE 可作为估算儿科头部 CT 检查中患者特定器官剂量的良好指标。对于皮肤(R2=0.99)、大脑(R2=0.98)和眼睛(R2=0.97),分别发现吸收剂量与 SSDE 之间存在很强的相关性。此外,还观察到 SSDE 与扫描范围外的红骨髓(扩展组织)的吸收剂量之间存在良好的相关性(R2=0.94)。本研究中获得的 SSDE 到器官剂量的转换系数提供了一种估算患者特定头部 CT 器官剂量的实用方法。