Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Faculty of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Phys Chem Chem Phys. 2020 Oct 7;22(38):21646-21650. doi: 10.1039/d0cp03805a.
We report the dynamics of lipid droplet formation induced by introducing cis- and/or trans-fatty acids into cells. Raman imaging allows the chemical analysis of each droplet, showing that exogenous fatty acids initially enter original endogenous droplets, then induce additional droplets containing endogenous lipids, and finally form their droplets.
我们报告了引入顺式和/或反式脂肪酸诱导脂滴形成的动力学。拉曼成像允许对每个液滴进行化学分析,表明外源性脂肪酸最初进入原始的内源性液滴,然后诱导含有内源性脂质的额外液滴,最后形成它们的液滴。