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评估 COVID-19 患者的噬血细胞性淋巴组织细胞增生症 H 评分。

Assessment of the Hemophagocytic Lymphohistiocytosis HScore in Patients With Coronavirus Disease 2019.

机构信息

Department for Rheumatology and Connective Tissue Diseases, University College London, London, United Kingdom.

Department of Infectious Diseases, Royal Free Hospital London NHS Foundation Trust, London, United Kingdom.

出版信息

Clin Infect Dis. 2021 Nov 2;73(9):e3110-e3112. doi: 10.1093/cid/ciaa1463.

DOI:10.1093/cid/ciaa1463
PMID:32985664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7543356/
Abstract

The clinical manifestation of moderate to severe coronavirus disease 2019 (COVID-19) has parallels to secondary hemophagocytic lymphohistiocytosis (HLH) both clinically and based on molecular inflammatory response. We found no evidence to support the utility of risk-stratifying COVID-19 patients using risk scoring methodology designed for HLH.

摘要

中度至重度 2019 年冠状病毒病（COVID-19）的临床表现与继发性噬血细胞性淋巴组织细胞增生症（HLH）在临床上和基于分子炎症反应方面具有相似性。我们没有发现证据支持使用专为 HLH 设计的风险评分方法对 COVID-19 患者进行风险分层的效用。

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