Kalidindi Kalyan Kumar Varma, Bhat Mohd Rafiq, Gupta Mayank, Mannem Abhishek, Chhabra Harvinder Singh
Indian Spinal Injuries Centre, Vasant Kunj, New Delhi, India.
Int J Spine Surg. 2020 Aug;14(4):544-551. doi: 10.14444/7072. Epub 2020 Jul 31.
Ligamentum flavum cysts have been rarely described in the literature and are one of the rare causes of neural compression and canal stenosis. Very few cases of their association with neurologic deficits are reported to date, and association with acute onset weakness is even rarer.
We report our experience with 3 cases of ligamentum flavum cyst that presented with acute onset weakness and also present a comprehensive literature review on lumbar ligamentum flavum cysts reported to date. All 3 patients had symptoms of severe neurogenic claudication and presented to us with acute onset of motor weakness in lower limbs. Ligamentum flavum cyst was located in the midline in 2 cases and laterally in 1 case. We performed excision of the cyst and decompression with fusion in 2 cases and decompression alone in 1 case. All 3 cases had significant improvement in their neurologic status postoperatively. Histopathological examination confirmed ligamentum flavum cyst in all 3 cases. We performed a PUBMED and EMBASE database search using the MeSH (Medical Subject Headings) terms "ligamentum flavum" and "cysts" for articles published to April 2019. We could identify 7 studies describing 20 cases of lumbar ligamentum flavum cysts with motor weakness in the literature. Only 1 case had been described with an acute onset of weakness.
Ligamentum flavum cysts should remain in the differential diagnosis of a patient who has symptoms of lumbar canal stenosis and presents with acute onset of neurological deficits. Such patients have a good improvement with surgery.
黄韧带囊肿在文献中鲜有描述,是神经受压和椎管狭窄的罕见原因之一。迄今为止,很少有其与神经功能缺损相关的病例报道,与急性起病的肌无力相关的病例更是罕见。
我们报告了3例表现为急性起病肌无力的黄韧带囊肿病例的经验,并对迄今为止报道的腰椎黄韧带囊肿进行了全面的文献综述。所有3例患者均有严重神经源性间歇性跛行症状,并以急性下肢运动无力就诊。黄韧带囊肿2例位于中线,1例位于侧方。我们对2例患者进行了囊肿切除及减压融合术,对1例患者仅进行了减压术。所有3例患者术后神经功能均有显著改善。组织病理学检查证实所有3例均为黄韧带囊肿。我们使用医学主题词(MeSH)“黄韧带”和“囊肿”在PUBMED和EMBASE数据库中检索截至2019年4月发表的文章。我们在文献中发现7项研究描述了20例伴有运动无力的腰椎黄韧带囊肿病例。仅有1例描述为急性起病的肌无力。
对于有腰椎管狭窄症状且急性起病出现神经功能缺损的患者,黄韧带囊肿应保留在鉴别诊断中。此类患者手术治疗后改善良好。