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微创开放脊柱手术治疗转移性脊髓压迫症患者的疗效:单中心随机对照试验。

Minimal Access Open Spine Surgery in Patients With Metastatic Spinal Cord Compression - A One-Center Randomized Controlled Trial.

机构信息

Spine Unit, Department of Orthopedic Surgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

Spine Unit, Department of Orthopedic Surgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

出版信息

Anticancer Res. 2020 Oct;40(10):5673-5678. doi: 10.21873/anticanres.114581.

DOI:10.21873/anticanres.114581
PMID:32988892
Abstract

BACKGROUND/AIM: We conducted a randomized controlled trial to investigate whether minimally access spine surgery (MASS) is less morbid than open surgery (OS) in patients with metastatic spinal cord compression (MSCC).

PATIENTS AND METHODS

A total of 49 MSCC patients were included in the trial. The outcome measures were bleeding (L), operation time (min), re-operations and prolonged wound healing.

RESULTS

The median age was 67 years (range=42-85 years) and 40% were men. The peri-operative blood loss in the MASS-group was significantly lower than that in the OS-group; 0.175L vs. 0.500L, (p=0.002). The median operation time for MASS was 142 min (range=72-203 min) vs. 103 (range=59-435 min) for OS (p=0.001). There was no significant difference between the two groups concerning revision surgery or delayed wound healing.

CONCLUSION

The MASS technique in MSCC patients is associated with less blood loss, but a longer operation time when compared to the OS technique.

摘要

背景/目的:我们进行了一项随机对照试验,以调查微创脊柱手术(MASS)是否比开放性手术(OS)在转移性脊髓压迫症(MSCC)患者中创伤更小。

患者和方法

共有 49 例 MSCC 患者参与了该试验。观察指标包括出血量(L)、手术时间(min)、再次手术和伤口愈合时间延长。

结果

患者的中位年龄为 67 岁(范围为 42-85 岁),其中 40%为男性。MASS 组围手术期出血量明显少于 OS 组;0.175L 比 0.500L,(p=0.002)。MASS 组的中位手术时间为 142min(范围为 72-203min),OS 组为 103min(范围为 59-435min)(p=0.001)。两组在再次手术或伤口愈合延迟方面无显著差异。

结论

与 OS 技术相比,MASS 技术在 MSCC 患者中可减少出血量,但手术时间更长。

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