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成人斯蒂尔病合并血栓性血小板减少性紫癜:病例报告及文献复习。

Adult-onset Still's disease with concurrent thrombotic thrombocytopenic purpura: case report and literature review.

机构信息

Division of Respiratory Medicine and Rheumatology, Department of Multidisclplinary Internal Medicine, Faculty of Medicine, Tottori University Hospital, Yonago, Tottori, Japan.

Department of Respiratory Medicine, Yonago Medical Centre, National Hospital Organisation Yonago Medical Center, Yonago, Tottori, Japan.

出版信息

BMJ Case Rep. 2020 Sep 28;13(9):e235786. doi: 10.1136/bcr-2020-235786.

Abstract

Thrombotic thrombocytopenic purpura (TTP) is rare complication resulting from adult-onset Still's disease (AOSD). We report the case of a 69-year-old Japanese man who initially presented with fever and joint pain and was diagnosed as having concurrent AOSD with TTP 1 month later. He had extremely high ferritin levels (32 696 ng/mL). He initially responded to plasma exchange but subsequently died of septic shock. AOSD accompanied by extremely high ferritin levels might be considered a sign of concurrent TTP.

摘要

血栓性血小板减少性紫癜(TTP)是一种罕见的并发症,可由成人Still 病(AOSD)引起。我们报告了一例 69 岁日本男性,最初表现为发热和关节痛,1 个月后诊断为 AOSD 合并 TTP。他的铁蛋白水平极高(32696ng/mL)。他最初对血浆置换有反应,但随后死于感染性休克。伴有极高铁蛋白水平的 AOSD 可能被认为是并发 TTP 的标志。

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本文引用的文献

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Case report of atypical Still's disease: a diagnosis of exclusion.非典型斯蒂尔病病例报告:排除性诊断。
Int Med Case Rep J. 2016 Oct 19;9:321-324. doi: 10.2147/IMCRJ.S117664. eCollection 2016.

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