Forensic Science SA and School of Medicine, The University of Adelaide, Australia.
Med Sci Law. 2021 Jan;61(1):69-72. doi: 10.1177/0025802420962353. Epub 2020 Sep 29.
Two cases of recently diagnosed oesophageal squamous-cell carcinomas in men, both aged 72 years, are reported that resulted in rapid clinical deterioration and death from upper-airway occlusion and haemorrhage, respectively. In the first case, direct growth of the tumour from metastatic deposits in the paratracheal lymph nodes through the wall of the trachea resulted in lethal acute airway occlusion. In the second case, local extension of the tumour through the wall of the oesophagus into the adjacent aorta resulted in an aorto-oesophageal fistula which led to catastrophic and fatal haemorrhage. Although rare, oesophageal squamous-cell carcinomas may cause unexpected death due to quite different mechanisms, and result in the need for a detailed medico-legal assessment.
报告两例最近诊断的食管鳞状细胞癌男性病例，年龄均为 72 岁，分别因上呼吸道阻塞和出血导致快速临床恶化和死亡。在第一个病例中，肿瘤直接从气管壁的气管旁淋巴结转移灶生长，导致致命性急性气道阻塞。在第二个病例中，肿瘤通过食管壁局部扩展到相邻的主动脉，导致发生主动脉-食管瘘，导致灾难性和致命性出血。尽管罕见，但食管鳞状细胞癌可能由于完全不同的机制导致意外死亡，需要进行详细的医学法律评估。
