患有阿尔波特综合征患者的同种异体移植抗肾小球基底膜肾小球肾炎。
Allograft antiglomerular basement membrane glomerulonephritis in a patient with Alport's syndrome.
作者信息
Teruel J L, Liaño F, Mampaso F, Moreno J, Serrano A, Quereda C, Ortuño J
出版信息
Nephron. 1987;46(1):43-4. doi: 10.1159/000184294.
PMID:3299117
Abstract
A patient with Alport's syndrome and chronic renal failure received a cadaver kidney graft. Six months after the transplantation he developed 'de novo' crescentic glomerulonephritis mediated by antiglomerular basement membrane antibodies. This rare complication may be attributed to sensitization against usual antigenic determinants of the graft glomerular basement membrane.
摘要
一名患有阿尔波特综合征和慢性肾衰竭的患者接受了尸体肾移植。移植后六个月，他出现了由抗肾小球基底膜抗体介导的“新发”新月体性肾小球肾炎。这种罕见的并发症可能归因于对移植肾肾小球基底膜常见抗原决定簇的致敏。
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