Sun Jinfeng, Zhang Jing, Dai Yunhai, Wan Xiaomei, Xie Lixin
Qingdao Eye Hospital, State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong First Medical University & Shandong Academy of Medical Sciences, Qingdao.
Department of Ophthalmology, Yantaishan Hospital, Yantai, Shandong.
Medicine (Baltimore). 2020 Sep 25;99(39):e22140. doi: 10.1097/MD.0000000000022140.
To observe the ocular axis, visual acuity and intraocular pressure (IOP) of aphakic eye in infants with congenital cataract and complex microphthalmos after first-stage cataract surgery.This retrospective study included infants with congenital cataract and operated at the Qingdao Eye Hospital between January 2010 and December 2014. The infants were divided into 2 groups: preoperative axial length <18 mm (microphthalmos) or ≥18 mm (controls). Follow-up lasted 24 months; visual acuity, axial length, and IOP were evaluated.There were 28 infants (55 eyes) in the microphthalmos group and 35 (61 eyes) in the control group. The preoperative visual acuity was negative for optokinetic nystagmus, while the postoperative visual acuity was positive for optokinetic nystagmus in both groups. The growth rate was higher in the microphthalmos group (1.4 ± 0.8 vs 0.8 ± 0.4 mm/yr, P < .001 vs controls). The axial length was smaller in the microphthalmos group at all time points compared with the control group (all P < .001). There was no changes in IOP in the microphthalmos group from baseline to 24 months (P = .147), but the IOP was slightly decreased in the control group (P = .015).Cataract surgery may contribute to ocular axis growth in infants with complex microphthalmos.
观察先天性白内障合并复杂性小眼球婴儿一期白内障手术后无晶状体眼的眼轴、视力及眼压。本回顾性研究纳入2010年1月至2014年12月在青岛眼科医院接受手术的先天性白内障婴儿。将婴儿分为2组:术前眼轴长度<18 mm(小眼球)或≥18 mm(对照组)。随访持续24个月;评估视力、眼轴长度和眼压。小眼球组有28例婴儿(55只眼),对照组有35例(61只眼)。两组术前视动性眼球震颤视力均为阴性,术后视动性眼球震颤视力均为阳性。小眼球组的生长率更高(1.4 ± 0.8 vs 0.8 ± 0.4 mm/年,与对照组相比P < .001)。与对照组相比,小眼球组在所有时间点的眼轴长度均较小(所有P < .001)。小眼球组从基线到24个月眼压无变化(P = .147),但对照组眼压略有下降(P = .015)。白内障手术可能有助于复杂性小眼球婴儿的眼轴生长。