Department of Radiation Oncology, Kayseri City Hospital, Kayseri, Turkey.
Cancer Biother Radiopharm. 2021 May;36(4):305-306. doi: 10.1089/cbr.2020.4211. Epub 2020 Sep 30.
In this article, it was examined whether the combined application of nanoparticle-based radiosensitizers with radiotherapy is beneficial. Nanoparticular or nanoparticle-based radiosensitizers appear promising in terms of feasibility, safety, and efficacy, as evidenced by preliminary results of ongoing studies. However, this method has its own advantages and disadvantages. According to current knowledge, it is impossible to mention that this method is the definitive treatment method because cancer is an individual disease and the treatments may differ from person to person. With the studies to be done, the application methods of optimal combinations with radiotherapy should be defined.
本文探讨了基于纳米粒子的放射增敏剂与放射疗法联合应用是否有益。基于纳米粒子的放射增敏剂在可行性、安全性和疗效方面具有很大的潜力,这一点可以从正在进行的研究的初步结果中得到证明。然而,这种方法有其自身的优缺点。根据目前的知识,不能说这种方法是明确的治疗方法,因为癌症是一种个体疾病,治疗方法可能因人而异。随着进一步的研究,应该确定与放射疗法联合应用的最佳组合的方法。