Department of Anesthesia and Critical Care, University of Chicago, Chicago, Illinois.
Center for Health and Social Sciences, the University of Chicago, Chicago, Illinois.
JAMA Cardiol. 2021 Jan 1;6(1):13-20. doi: 10.1001/jamacardio.2020.4311.
Cardiac stress testing is often performed prior to noncardiac surgery, although trends in use of preoperative stress testing and the effect of testing on cardiovascular outcomes are currently unknown.
To describe temporal trends and outcomes of preoperative cardiac stress testing from 2004 to 2017.
DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional study of patients undergoing elective total hip or total knee arthroplasty from 2004 to 2017. Trend analysis was conducted using Joinpoint and generalized estimating equation regression. The study searched IBM MarketScan Research Databases inpatient and outpatient health care claims for private insurers including supplemental Medicare coverage and included patients with a claim indicating an elective total hip or total knee arthroplasty from January 1, 2004, to December 31, 2017.
Elective total hip or knee arthroplasty.
Trend in yearly frequency of preoperative cardiac stress testing.
The study cohort consisted of 801 396 elective total hip (27.9%; n = 246 168 of 801 396) and total knee (72.1%; 555 228 of 801 396) arthroplasty procedures, with a median age of 62 years (interquartile range, 57-70 years) and 58.1% women (n = 465 545 of 801 396). The overall rate of stress testing during the study period was 10.4% (n = 83 307 of 801 396). The rate of stress tests increased 0.65% (95% CI, 0.09-1.21; P = .03) annually from quarter (Q) 1 of 2004 until Q2 of 2006. A joinpoint was identified at Q3 of 2006 (95% CI, 2005 Q4 to 2007 Q4) when preoperative stress test use decreased by -0.71% (95% CI, -0.79% to 0.63%; P < .001) annually. A second joinpoint was identified at the Q4 of 2013 (95% CI, 2011 Q3 to 2015 Q3), when the decline in stress testing rates slowed to -0.40% (95% CI, -0.57% to -0.24%; P < .001) annually. The overall rate of myocardial infarction and cardiac arrest was 0.24% (n = 1677 of 686 067). Rates of myocardial infraction and cardiac arrest were not different in patients with at least 1 Revised Cardiac Risk Index condition who received a preoperative stress test and those who did not (0.60%; n = 221 of 36 554 vs 0.57%; n = 694 of 122 466; P = .51).
The frequency of preoperative stress testing declined annually from 2006 through 2017. Among patients with at least 1 Revised Cardiac Risk Index condition, no difference was observed in cardiovascular outcomes between patients who did and did not undergo preoperative testing.
在非心脏手术前,通常会进行心脏应激测试,尽管目前尚不清楚术前应激测试的使用趋势及其对心血管结果的影响。
描述 2004 年至 2017 年期间术前心脏应激测试的时间趋势和结果。
设计、设置和参与者:这是一项对 2004 年至 2017 年接受择期全髋关节或全膝关节置换术的患者进行的横断面研究。使用 Joinpoint 和广义估计方程回归进行趋势分析。该研究在 IBM MarketScan Research Databases 中搜索了私人保险公司的住院和门诊医疗保健索赔,包括补充医疗保险覆盖范围,并包括有择期全髋关节或全膝关节置换术索赔的患者,从 2004 年 1 月 1 日至 2017 年 12 月 31 日。
择期全髋关节或膝关节置换术。
术前心脏应激测试每年频率的趋势。
研究队列包括 801396 例择期全髋关节(27.9%;n=246168/801396)和全膝关节(72.1%;n=555228/801396)关节置换手术,中位年龄为 62 岁(四分位间距,57-70 岁),58.1%为女性(n=465545/801396)。研究期间应激测试的总发生率为 10.4%(n=83307/801396)。从 2004 年第一季度(Q1)到 2006 年第二季度(Q2),应激测试的发生率每年增加 0.65%(95%CI,0.09-1.21;P=0.03)。在 2006 年第三季度(95%CI,2005 年第四季度至 2007 年第四季度)确定了一个联合点,每年术前应激测试的使用率下降了-0.71%(95%CI,-0.79%至 0.63%;P<0.001)。在 2013 年第四季度(95%CI,2011 年第三季度至 2015 年第三季度)确定了第二个联合点,应激测试率的下降速度放缓至-0.40%(95%CI,-0.57%至-0.24%;P<0.001)。心肌梗死和心脏骤停的总发生率为 0.24%(n=686067/1677)。在至少有 1 个修订后的心脏风险指数(Revised Cardiac Risk Index,RCRI)条件且接受术前应激测试的患者与未接受术前应激测试的患者中,心肌梗死和心脏骤停的发生率没有差异(0.60%;n=36554/221 vs 0.57%;n=122466/694;P=0.51)。
从 2006 年到 2017 年,术前应激测试的频率每年都在下降。在至少有 1 个修订后的心脏风险指数条件的患者中,接受和未接受术前测试的患者在心血管结果方面没有差异。