Mathisen J R, Giunta F, Marini G, Backlund E O
Surg Neurol. 1987 Aug;28(2):100-4. doi: 10.1016/0090-3019(87)90080-2.
Utilizing the Leksell stereotactic system, the transcerebellar approach was used for posterior fossa biopsies. During a period of 12 years, a total of 29 patients were operated on by this technique, among them 12 children. In the adult, the procedure was carried out with the patient awake and sitting upright; the pediatric patients required general anesthesia and the head was supported either manually or by a clamp. Representative specimens were obtained in all cases but one, showing a wide diagnostic spectrum. As a rule, the procedures were performed smoothly, with no serious side effects. Stereotactic biopsies in the posterior fossa, hitherto seldom performed, open new diagnostic perspectives, one of which is for use in obscure brain stem lesions. The transcerebellar approach has been proven to be easy, direct, and safe provided an appropriate technique is used, such as that described in the present paper.
利用Leksell立体定向系统，采用经小脑入路进行后颅窝活检。在12年的时间里，共有29例患者接受了该技术手术，其中12例为儿童。对于成人患者，手术在患者清醒且坐姿直立的状态下进行；儿科患者则需要全身麻醉，头部由人工或夹具支撑。除1例病例外，所有病例均获取了具有代表性的标本，显示出广泛的诊断范围。通常情况下，手术进行顺利，无严重副作用。后颅窝立体定向活检此前很少进行，它开辟了新的诊断前景，其中之一是用于不明原因的脑干病变。经小脑入路已被证明是简便、直接且安全的，前提是采用适当的技术，如本文所述的技术。
