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精神科药物在急诊科儿科精神卫生患者中的应用。

Psychotropic medication use for paediatric mental health patients in an emergency department.

机构信息

Emergency Department, The Royal Children's Hospital, Melbourne, Victoria, Australia.

Emergency Research, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.

出版信息

Emerg Med Australas. 2021 Apr;33(2):292-301. doi: 10.1111/1742-6723.13617. Epub 2020 Sep 30.

Abstract

OBJECTIVE

There is paucity of evidence for psychotropic medication use in children and adolescents presenting with mental health (MH) problems to the ED. We set out to describe paediatric psychotropic medication use in the ED.

METHODS

We conducted a retrospective electronic medical record review of ED patients with MH discharge codes at a tertiary paediatric ED in 2018. We assessed the epidemiology and management of patients who received a psychotropic medication. We calculated the odds ratios (ORs with 95% confidence intervals [CIs]) of key demographic factors of medicated versus non-medicated MH patients.

RESULTS

During 2018 there were 1695 MH-related presentations to the ED. Of these, 280 presentations resulted in the patient receiving a psychotropic medication (16.5%). Medicated children with MH illness were more likely to be male (OR 1.50, 95% CI 1.16-1.96), have a more acute triage category (OR 3.37, 95% CI 2.28-4.98), have an ED length of stay greater than 12 h (OR 3.96, 95% CI 2.56-6.13) and present after hours (OR 1.51, 95% CI 1.16-1.96). Most had a diagnosis of acute behavioural disturbance or suicidal ideation. A variety of treatment regimens were used but children primarily received a single oral agent (diazepam or olanzapine). Parenteral medications were given in 8.6%. No adverse events were recorded.

CONCLUSION

A minority of children with MH presentations to the ED were medicated. It will require multicentre research to determine the most effective and safe acute psychotropic agents for oral and parenteral use in children in the ED.

摘要

目的

在因心理健康问题就诊于急诊科的儿童和青少年中,精神药物的使用证据有限。我们旨在描述急诊科儿科精神药物的使用情况。

方法

我们对 2018 年一家三级儿科急诊科有心理健康出院诊断代码的急诊科患者进行了回顾性电子病历审查。我们评估了接受精神药物治疗的患者的流行病学和管理情况。我们计算了接受与未接受精神药物治疗的心理健康患者的关键人口统计学因素的比值比(95%置信区间[CI])。

结果

2018 年,急诊科有 1695 例与心理健康相关的就诊。其中,280 例就诊的患者接受了精神药物治疗(16.5%)。患有心理健康疾病的接受药物治疗的儿童更有可能是男性(比值比 1.50,95%CI 1.16-1.96),分诊类别更急性(比值比 3.37,95%CI 2.28-4.98),急诊科留观时间超过 12 小时(比值比 3.96,95%CI 2.56-6.13),并且在非工作时间就诊(比值比 1.51,95%CI 1.16-1.96)。大多数患者的诊断为急性行为障碍或自杀意念。使用了各种治疗方案,但儿童主要接受单一口服药物(地西泮或奥氮平)。给予了 8.6%的静脉内药物。未记录到不良事件。

结论

在因心理健康问题就诊于急诊科的儿童中,只有少数接受了药物治疗。需要进行多中心研究,以确定在急诊科最有效和安全的儿童口服和静脉内急性精神药物。

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