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对导致先前未使用过阿片类药物的内科住院患者开具门诊阿片类药物处方的住院阿片类药物处方情况的评估。

Evaluation of Inpatient Opioid Prescribing Resulting in Outpatient Opioid Prescriptions for Previously Opioid-Naive Internal Medicine Patients.

作者信息

Perkins Bryce, Huckleberry Yvonne, Bogdanich Ivana, Leelathanalerk Areerut, Huckleberry April, Konecnik Michaela, Miller David C, Bailey Morgan, Bime Christian

机构信息

Department of Medicine, College of Medicine, University of Arizona, Tucson, AZ, USA.

Banner University Medical Center, Tucson, AZ, USA.

出版信息

J Pharm Pract. 2022 Apr;35(2):179-183. doi: 10.1177/0897190020961290. Epub 2020 Oct 1.

Abstract

BACKGROUND

Little data exist regarding inpatient opioid prescriptions as a potential contribution to the current opioid crisis. While pain management is essential to inpatient care, the ease of which opioids may be prescribed for all levels of pain may contribute to unnecessary inpatient exposure and new outpatient prescriptions. The aim of this study was to observe patterns of opioid prescribing potentially leading to new opioid prescriptions at hospital discharge for previously opioid-naive patients.

METHODS

This study was a single-center observational study of opioid-naïve internal medicine patients who were prescribed inpatient opioids. Patient charts were reviewed to assess the patterns of inpatient opioid and non-opioid analgesic use, new opioid prescriptions upon discharge and medical record documentation justifying the need for outpatient therapy.

RESULTS

Among the 101 patients included in this study, 71 were prescribed IV opioids and 45 were prescribed both IV and oral opioids. Non-opioid analgesics were available for 78 patients. Twenty patients were discharged with a new prescription. The mean duration of outpatient prescriptions was 3.85 +/- 1.85 days with mean morphine milligram equivalents (MME) of 44.25 +/- 22.16. Among patients receiving these outpatient prescriptions, 11 had reference to the therapy in the discharge summary.

CONCLUSIONS

This observational study describes an opportunity to improve inpatient opioid prescribing practices which may reduce new prescriptions for continued outpatient therapy. Further work should focus on optimizing use of non-opioid analgesia, minimizing use of IV opioids and requiring prescribers to justify the indication for new opioid prescriptions upon hospital discharge.

摘要

背景

关于住院患者阿片类药物处方作为当前阿片类药物危机潜在因素的数据很少。虽然疼痛管理对住院治疗至关重要,但阿片类药物可用于各种程度疼痛的便利性可能会导致患者不必要地接触阿片类药物,并产生新的门诊处方。本研究的目的是观察阿片类药物处方模式,这些模式可能导致之前未使用过阿片类药物的患者在出院时产生新的阿片类药物处方。

方法

本研究是一项对接受住院阿片类药物治疗的未使用过阿片类药物的内科患者进行的单中心观察性研究。查阅患者病历以评估住院阿片类药物和非阿片类镇痛药的使用模式、出院时的新阿片类药物处方以及证明门诊治疗必要性的病历记录。

结果

本研究纳入的101例患者中,71例接受静脉注射阿片类药物治疗,45例同时接受静脉注射和口服阿片类药物治疗。78例患者可使用非阿片类镇痛药。20例患者出院时开具了新处方。门诊处方的平均持续时间为3.85 +/- 1.85天,平均吗啡毫克当量(MME)为44.25 +/- 22.16。在接受这些门诊处方的患者中,11例在出院小结中有关于该治疗的记录。

结论

这项观察性研究描述了一个改善住院阿片类药物处方实践的机会,这可能会减少持续门诊治疗的新处方。进一步的工作应集中在优化非阿片类镇痛的使用、尽量减少静脉注射阿片类药物的使用,并要求开处方者说明出院时开具新阿片类药物处方的适应症。

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