Laniado Nadia, Hersh Elliot V, Badner Victor M, Saraghi Mana
Assistant Professor, Department of Dentistry and Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York.
Professor, Oral Surgery and Pharmacology, Director, Division of Pharmacology, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania.
Compend Contin Educ Dent. 2020 Oct;41(9):466-473; quiz 474.
It is well-known that there is an opioid crisis in the United States. Prescription opioid analgesics contribute to this crisis; in 2012, dentists ranked second to family care physicians as the top prescribers. The medical and dental literature demonstrates that dental prescribing practices have been excessive, resulting in leftover medication that could then be diverted, misused, or abused. A multimodal analgesic approach is highly valuable in targeting pain along various points on the peripheral and central pain pathways and includes the use of long-acting local anesthetics, nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen, and opioids, the last of which are generally reserved for the most severe pain only. The Dental Impaction Pain Model demonstrates that NSAIDs are the frontline drugs for postoperative dental pain. Opioids have their role in postoperative analgesia but should be reserved for severe breakthrough pain or in situations where NSAIDs may be contraindicated.
众所周知,美国存在阿片类药物危机。处方阿片类镇痛药加剧了这场危机;2012年,牙医作为主要开方者仅次于家庭护理医生,排名第二。医学和牙科文献表明,牙科开方行为过度,导致剩余药物可能被转移、误用或滥用。多模式镇痛方法对于针对外周和中枢疼痛通路各点的疼痛非常有价值,包括使用长效局部麻醉剂、非甾体抗炎药(NSAIDs)、对乙酰氨基酚和阿片类药物,其中最后一种通常仅用于最严重的疼痛。牙阻生疼痛模型表明,NSAIDs是术后牙齿疼痛的一线药物。阿片类药物在术后镇痛中发挥作用,但应保留用于严重的突破性疼痛或NSAIDs可能禁忌的情况。