• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

为艾滋病毒/艾滋病感染者提供住房稳定和病毒抑制的途径:“为多重诊断的艾滋病毒阳性无家可归人群建立医疗之家”倡议的研究结果。

Pathways to housing stability and viral suppression for people living with HIV/AIDS: Findings from the Building a Medical Home for Multiply Diagnosed HIV-positive Homeless Populations initiative.

机构信息

Department of Public Health, Zuckerberg College of Health Sciences, Univeristy of Massachusetts, Lowell, Lowell, MA, United States of America.

Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.

出版信息

PLoS One. 2020 Oct 1;15(10):e0239190. doi: 10.1371/journal.pone.0239190. eCollection 2020.

DOI:10.1371/journal.pone.0239190
PMID:33001986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7529314/
Abstract

BACKGROUND

People with HIV with co-occurring substance use and mental health diagnoses who are unstably housed have poorer outcomes for retention in care and viral suppression. Navigation models are a potential strategy to help this vulnerable population obtain the necessary medical and non-medical services across multiple service systems. The Health Resources and Services Administration's Special Projects of National Significance: "Building a Medical Home for Multiply-Diagnosed HIV-positive Homeless Populations initiative 2012-2017 found that navigation models may be an effective intervention to support people with HIV with unstable housing improve HIV health outcomes. However, there is limited information about the mechanisms by which this intervention works. In this article, we explore the participant and program factors for achieving stable housing at 6 months and how these factors influence HIV health outcomes.

METHODS AND FINDINGS

This was a prospective study of 471 unstably housed people with HIV enrolled in a navigation intervention across nine sites in the United Stated from 2013-2017. All sites provided HIV primary medical care. Eight sites were located in urban areas and one site served a predominantly rural population. Two sites were federally qualified health centers, three were city or county health departments, one site was a comprehensive HIV/AIDS service organization, and three sites were outpatient or mobile clinics affiliated with a university -based or hospital system. Data were collected via interview and medical chart review at baseline, post 6 and 12 months. Type and dose of navigation activities were collected via a standardized encounter form. We used a path analysis model with housing stability at 6 months as the mediator to examine the direct and indirect effects of participant's socio-demographics and risk factors and navigation on viral suppression and retention in care at 12 months. Housing stability at 6 months was associated with male gender, younger age, viral suppression at baseline, having a lower risk for opiate use, recent homelessness, lower risk of food insecurity, and a longer length of time living with HIV. Participants who increased self-efficacy with obtaining help by 6 months had significantly higher odds of achieving housing stability. Stable housing, fewer unmet needs, moderate to high risk for opiate use, and viral suppression at baseline had a direct effect on viral suppression at 12 months. The intensity of navigation contact had no direct effect on housing stability and a mixed direct effect on viral suppression. Recent diagnosis with HIV, women, greater social support, increased self-efficacy and higher intensity of navigation contact had a direct effect on improved retention in HIV primary care at 12 months.

CONCLUSIONS

In this sample of people with HIV who are experiencing homelessness, housing stability had a significant direct path to viral suppression. Navigation activities did not have a direct effect on the path to housing stability but were directly related to retention in care. These results identify key populations and factors to target resources and policies for addressing the health and social unmet needs of people with HIV to achieve housing stability and HIV health outcomes.

摘要

背景

同时患有物质使用障碍和精神健康问题且居住不稳定的艾滋病毒感染者,其在医疗保健机构中的保留率和病毒抑制率均较差。导航模式是一种潜在的策略,可以帮助这一脆弱群体在多个服务系统中获得必要的医疗和非医疗服务。卫生资源和服务管理局的特别项目具有国家意义:“为多重诊断的艾滋病毒阳性无家可归者建立医疗之家倡议 2012-2017 年发现,导航模式可能是支持居住不稳定的艾滋病毒感染者改善艾滋病毒健康结果的有效干预措施。然而,关于该干预措施的作用机制的信息有限。在本文中,我们探讨了在 6 个月时实现稳定住房的参与者和计划因素,以及这些因素如何影响艾滋病毒健康结果。

方法和发现

这是一项在美国 9 个地点进行的前瞻性研究,共有 471 名居住不稳定的艾滋病毒感染者参与了一项导航干预措施,研究时间为 2013-2017 年。所有地点均提供艾滋病毒初级医疗服务。8 个地点位于城市地区,1 个地点服务于主要农村人口。2 个地点是联邦合格的健康中心,3 个是城市或县卫生部门,1 个是综合艾滋病毒/艾滋病服务组织,3 个是与大学或医院系统相关的门诊或流动诊所。数据通过访谈和医疗记录审查在基线、6 个月和 12 个月时收集。通过标准化的就诊表收集导航活动的类型和剂量。我们使用路径分析模型,以 6 个月时的住房稳定性作为中介,来检验参与者的社会人口统计学和风险因素以及导航对 12 个月时病毒抑制和医疗保健保留率的直接和间接影响。6 个月时的住房稳定性与男性、年轻、基线时病毒抑制、较低的阿片类药物使用风险、最近无家可归、较低的食物不安全风险以及较长的艾滋病毒感染时间有关。6 个月时自我效能感提高以获得帮助的参与者,其获得住房稳定的几率显著增加。6 个月时的稳定住房、较少的未满足需求、中等到高度的阿片类药物使用风险以及基线时的病毒抑制对 12 个月时的病毒抑制有直接影响。导航接触的强度对住房稳定没有直接影响,对病毒抑制有混合的直接影响。最近被诊断出患有艾滋病毒、女性、更大的社会支持、自我效能感的提高以及更高强度的导航接触对 12 个月时改善艾滋病毒初级保健的保留率有直接影响。

结论

在这个经历无家可归的艾滋病毒感染者样本中,住房稳定与病毒抑制有显著的直接关系。导航活动对住房稳定的路径没有直接影响,但与保留在护理中直接相关。这些结果确定了关键人群和因素,以便针对艾滋病毒感染者的健康和社会未满足需求分配资源和政策,以实现住房稳定和艾滋病毒健康结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bae/7529314/5a706d5c3879/pone.0239190.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bae/7529314/e702ce089dbb/pone.0239190.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bae/7529314/5a706d5c3879/pone.0239190.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bae/7529314/e702ce089dbb/pone.0239190.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bae/7529314/5a706d5c3879/pone.0239190.g002.jpg

相似文献

1
Pathways to housing stability and viral suppression for people living with HIV/AIDS: Findings from the Building a Medical Home for Multiply Diagnosed HIV-positive Homeless Populations initiative.为艾滋病毒/艾滋病感染者提供住房稳定和病毒抑制的途径:“为多重诊断的艾滋病毒阳性无家可归人群建立医疗之家”倡议的研究结果。
PLoS One. 2020 Oct 1;15(10):e0239190. doi: 10.1371/journal.pone.0239190. eCollection 2020.
2
The Role of Patient Navigators in Building a Medical Home for Multiply Diagnosed HIV-Positive Homeless Populations.患者导航员在为多重诊断的艾滋病毒阳性无家可归人群建立医疗之家方面的作用。
J Public Health Manag Pract. 2017 May/Jun;23(3):276-282. doi: 10.1097/PHH.0000000000000512.
3
The Influence of Housing Status on the HIV Continuum of Care: Results From a Multisite Study of Patient Navigation Models to Build a Medical Home for People Living With HIV Experiencing Homelessness.住房状况对HIV连续护理的影响:一项多地点研究的结果,该研究旨在探讨为感染HIV的无家可归者建立医疗之家的患者导航模式。
Am J Public Health. 2018 Dec;108(S7):S539-S545. doi: 10.2105/AJPH.2018.304736.
4
Predictors of CD4 health and viral suppression outcomes for formerly homeless people living with HIV/AIDS in scattered site supportive housing.在分散式支持性住房中,感染艾滋病毒/艾滋病的前无家可归者的CD4健康状况和病毒抑制结果的预测因素。
AIDS Care. 2017 Nov;29(11):1458-1462. doi: 10.1080/09540121.2017.1307920. Epub 2017 Mar 23.
5
Unmet Needs Among Out of Care and Recently Diagnosed Women of Color With HIV: Opportunities for Focused Interventions.处于关怀之外和最近被诊断患有 HIV 的有色人种女性的未满足需求:重点干预的机会。
J Public Health Manag Pract. 2022;28(2):135-142. doi: 10.1097/PHH.0000000000001243.
6
Socioeconomic, Behavioral, and Clinical Characteristics of Persons Living with HIV Who Experience Homelessness in the United States, 2015-2016.2015-2016 年美国无家可归的 HIV 感染者的社会经济、行为和临床特征。
AIDS Behav. 2020 Jun;24(6):1701-1708. doi: 10.1007/s10461-019-02704-4.
7
Peer Support and the HIV Continuum of Care: Results from a Multi-Site Randomized Clinical Trial in Three Urban Clinics in the United States.同伴支持与 HIV 连续护理:来自美国三个城市诊所的一项多中心随机临床试验结果。
AIDS Behav. 2018 Aug;22(8):2627-2639. doi: 10.1007/s10461-017-1999-8.
8
Housing Status, Medical Care, and Health Outcomes Among People Living With HIV/AIDS: A Systematic Review.艾滋病毒/艾滋病感染者的住房状况、医疗保健及健康结果:一项系统综述
Am J Public Health. 2016 Jan;106(1):e1-e23. doi: 10.2105/AJPH.2015.302905. Epub 2015 Nov 12.
9
The impact of representative payee services on medication adherence among unstably housed people living with HIV/AIDS.代付人服务对不稳定住房的艾滋病毒/艾滋病感染者药物依从性的影响。
AIDS Care. 2016;28(3):384-9. doi: 10.1080/09540121.2015.1093073. Epub 2015 Oct 7.
10
Advancing Patient Navigation for HIV: Evaluating Models of Care for Housing and Employment.推进艾滋病毒患者导航服务:评估住房和就业护理模式。
AIDS Behav. 2024 Nov;28(11):3910-3918. doi: 10.1007/s10461-024-04464-2. Epub 2024 Aug 22.

引用本文的文献

1
"A cure might help, but it won't erase it all": a qualitative study of policy challenges and priorities for long-term survivors of HIV in the United States.“治愈或许会有帮助,但无法消除一切”:对美国HIV长期存活者面临的政策挑战与优先事项的定性研究
J Int AIDS Soc. 2025 Jul;28(7):e70006. doi: 10.1002/jia2.70006.
2
Exploring the Association Between Indicators of Socioeconomic Instability, Survival Sex, and Methamphetamine Use Among Young Adult Black Gay, Bisexual, and Other Men Who Have Sex With Men: A Cross-Sectional Study.探索社会经济不稳定指标、生存性性行为与年轻成年黑人男同性恋、双性恋和其他与男性发生性关系者(MSM)中使用甲基苯丙胺之间的关联:一项横断面研究。
J Assoc Nurses AIDS Care. 2023;34(6):538-547. doi: 10.1097/JNC.0000000000000428. Epub 2023 Sep 22.
3

本文引用的文献

1
Longitudinal Determinants of Housing Stability Among People Living With HIV/AIDS Experiencing Homelessness.感染艾滋病毒/艾滋病且无家可归者住房稳定性的纵向决定因素
Am J Public Health. 2018 Dec;108(S7):S552-S560. doi: 10.2105/AJPH.2018.304772.
2
The Influence of Housing Status on the HIV Continuum of Care: Results From a Multisite Study of Patient Navigation Models to Build a Medical Home for People Living With HIV Experiencing Homelessness.住房状况对HIV连续护理的影响:一项多地点研究的结果,该研究旨在探讨为感染HIV的无家可归者建立医疗之家的患者导航模式。
Am J Public Health. 2018 Dec;108(S7):S539-S545. doi: 10.2105/AJPH.2018.304736.
3
The CARES Program: Improving Viral Suppression and Retention in Care Through a Comprehensive Team-Based Approach to Care for People with HIV and Complex Psychosocial Needs.CARES 项目:通过全面的团队护理方法改善艾滋病毒感染者和复杂心理社会需求人群的病毒抑制和保留率。
AIDS Patient Care STDS. 2023 Aug;37(8):416-424. doi: 10.1089/apc.2023.0061.
4
The Impact of the COVID-19 Pandemic on HIV-Positive Men Who Have Sex With Men: (Dis)connection to Social, Sexual, and Health Networks.2019年冠状病毒病疫情对男男性行为艾滋病毒感染者的影响:与社会、性和健康网络的(脱)连接
Psychol Sex. 2023;14(1):306-320. doi: 10.1080/19419899.2022.2112745. Epub 2022 Aug 17.
5
HIV care cascade for women living with HIV in the Greater Toronto Area versus the rest of Ontario and Canada.安大略省大多伦多地区与安大略省其他地区和加拿大的 HIV 感染妇女的 HIV 护理链。
Int J STD AIDS. 2023 Jan;34(1):4-17. doi: 10.1177/09564624221108034. Epub 2022 Nov 21.
6
Outcomes of the KC life 360 intervention: Improving employment and housing for persons living with HIV.KC 生活 360 干预的结果:改善艾滋病毒感染者的就业和住房状况。
PLoS One. 2022 Sep 16;17(9):e0274923. doi: 10.1371/journal.pone.0274923. eCollection 2022.
7
Does resource insecurity drive HIV-related stigma? Associations between food and housing insecurity with HIV-related stigma in cohort of women living with HIV in Canada.资源不安全是否会导致与艾滋病相关的污名化?加拿大艾滋病毒感染者队列中食物和住房不安全与艾滋病相关污名之间的关联。
J Int AIDS Soc. 2022 Jul;25 Suppl 1(Suppl 1):e25913. doi: 10.1002/jia2.25913.
8
Coordinating Systems of Care for HIV and Opioid Use Disorder: A Systematic Review of Enablers and Barriers to Integrated Service Access, and Systems and Tools Required for Implementation.协调针对艾滋病毒和阿片类药物使用障碍的护理系统:对综合服务获取的促进因素和障碍以及实施所需的系统和工具的系统评价。
Med Care Res Rev. 2022 Oct;79(5):618-639. doi: 10.1177/10775587211051182. Epub 2021 Oct 11.
Mobile Multidisciplinary HIV Medical Care for Hard-to-Reach Individuals Experiencing Homelessness in San Francisco.
为旧金山难以接触到的无家可归者提供移动多学科艾滋病毒医疗服务。
Am J Public Health. 2018 Dec;108(S7):S528-S530. doi: 10.2105/AJPH.2018.304732.
4
Reducing HIV-Related Health Disparities in the Health Resources and Services Administration's Ryan White HIV/AIDS Program.减少健康资源与服务管理署“瑞安·怀特艾滋病防治计划”中的艾滋病毒相关健康差异。
Am J Public Health. 2018 Nov;108(S4):S246-S250. doi: 10.2105/AJPH.2018.304689.
5
The effect of unstable housing on HIV treatment biomarkers: An instrumental variables approach.住房不稳定对 HIV 治疗生物标志物的影响:工具变量法。
Soc Sci Med. 2018 Oct;214:70-82. doi: 10.1016/j.socscimed.2018.07.051. Epub 2018 Aug 13.
6
Is HIV patient navigation associated with HIV care continuum outcomes?HIV 患者导航与 HIV 护理连续体结局相关吗?
AIDS. 2018 Nov 13;32(17):2557-2571. doi: 10.1097/QAD.0000000000001987.
7
Long-Term Supportive Housing is Associated with Decreased Risk for New HIV Diagnoses Among a Large Cohort of Homeless Persons in New York City.长期支持性住房与降低纽约市大量无家可归者中新发 HIV 诊断风险相关。
AIDS Behav. 2018 Sep;22(9):3083-3090. doi: 10.1007/s10461-018-2138-x.
8
Effectiveness of a Peer Navigation Intervention to Sustain Viral Suppression Among HIV-Positive Men and Transgender Women Released From Jail: The LINK LA Randomized Clinical Trial.同伴导航干预维持 HIV 阳性男性和出狱跨性别女性病毒抑制效果:LINK LA 随机临床试验。
JAMA Intern Med. 2018 Apr 1;178(4):542-553. doi: 10.1001/jamainternmed.2018.0150.
9
The Effect of Patient Navigation on the Likelihood of Engagement in Clinical Care for HIV-Infected Individuals Leaving Jail.患者导航对感染艾滋病毒的出狱个体参与临床护理可能性的影响。
Am J Public Health. 2018 Mar;108(3):385-392. doi: 10.2105/AJPH.2017.304250. Epub 2018 Jan 18.
10
Peer Support and the HIV Continuum of Care: Results from a Multi-Site Randomized Clinical Trial in Three Urban Clinics in the United States.同伴支持与 HIV 连续护理:来自美国三个城市诊所的一项多中心随机临床试验结果。
AIDS Behav. 2018 Aug;22(8):2627-2639. doi: 10.1007/s10461-017-1999-8.