Solmi L, Gandolfi L, Muratori R, Leo P, Bacchini P
Am J Gastroenterol. 1987 Aug;82(8):744-8.
Aim of this study was the evaluation of percutaneous echo-guided fine-needle biopsy in the diagnosis of focal lesions of the pancreas. In patients with masses of the pancreas 43 echo-guided fine-needle punctures have been performed. In 27 of the 30 cases of cancer, echo-guided puncture allowed aspiration of cells revealing malignancy. In the remaining three cases the histology was normal. Malignancy was not detected in the aspirate of any of the 13 cases of benign solid masses. In one of these patients we failed to obtain sufficient material for the purpose of diagnosis. The sensitivity of the method was 90%, the specificity 100%, and the diagnostic accuracy 92.8%. Positive and negative predictive values were 100 and 75%, respectively. No complications worthy of note occurred.
本研究的目的是评估经皮超声引导下细针穿刺活检在胰腺局灶性病变诊断中的应用。对胰腺肿块患者进行了43次超声引导下细针穿刺。在30例癌症病例中的27例，超声引导下穿刺能够获取显示恶性特征的细胞。其余3例组织学检查结果正常。13例良性实性肿块的抽吸物中均未检测到恶性病变。在其中1例患者中，我们未能获取足够用于诊断的材料。该方法的敏感性为90%，特异性为100%，诊断准确性为92.8%。阳性和阴性预测值分别为100%和75%。未发生值得注意的并发症。
