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小儿变应性真菌性鼻-鼻窦炎伴广泛颅内蔓延——病例报告及文献复习

Pediatric allergic fungal rhinosinusitis with extensive intracranial extension - Case report and literature review.

作者信息

Alenzi Haifa Lafi, Al Momen Ali, Molani Fadel

机构信息

Northern Border University, Saudi Arabia.

ENT, Rhinology & Skull Base Surgery Consultant at King Fahad Specialist Hospital, Dammam, Saudi Arabia.

出版信息

Int J Surg Case Rep. 2020;75:437-440. doi: 10.1016/j.ijscr.2020.09.049. Epub 2020 Sep 12.

Abstract

INTRODUCTION

Over the last two decades, allergic fungal sinusitis (AFRS) has become increasingly common. It's defined as a noninvasive, benign inflammatory fungal disease of the sinuses which develops in young adults and adolescents. Patients often complain of symptoms like nasal obstruction, congestion, purulent or clear rhinorrhea, anosmia, and headache. The cases are also presenting clinically with symptoms like epiphora and eye discharge as a result of nasolacrimal gland obstruction. In this article, we will review a unique case of AFRS, in an adolescent male. The case was diagnosed with intracranial extradural extension.

CASE REPORT

A 15 years old male with AFRS was diagnosed and managed. The case was diagnosed to have allergic fungal sinusitis based on Bent and Khun diagnostic criteria, presented with intracranial extradural extension.

DISCUSSION

In our case, there were no irreversible complications except a recurrent polyp. The case was mainly complaining of long-standing nasal discharge and on-off headache with no orbital complaint and no other neurological signs. This shows a presentation of the fungal sinusitis and the need for aggressive intervention for AFRS both medically and surgically for pediatric patients as well.

CONCLUSION

To conclude, despite AFRS being categorized as a benign, non-invasive disease, its presentation can range from simple nasal obstruction to signs and symptoms of intraorbital and/or intracranial complications; with pediatric cases being very aggressive. Careful clinical evaluation, detailed histopathological examination, navigation assisted endoscopic sinus surgery followed by steroid treatment, and a lifelong follow up to manage the recurrence.

摘要

引言

在过去二十年中,变应性真菌性鼻窦炎(AFRS)越来越常见。它被定义为鼻窦的一种非侵袭性、良性炎症性真菌病,多发生于青年人和青少年。患者常主诉鼻塞、流涕、脓性或清涕、嗅觉减退和头痛等症状。由于鼻泪管阻塞,这些病例临床上还会出现流泪和眼部分泌物等症状。在本文中,我们将回顾一例青少年男性AFRS的独特病例。该病例被诊断为颅内硬膜外扩展。

病例报告

一名15岁患有AFRS的男性被诊断并接受治疗。根据本特和坤的诊断标准,该病例被诊断为变应性真菌性鼻窦炎,并伴有颅内硬膜外扩展。

讨论

在我们的病例中,除了复发性息肉外,没有不可逆的并发症。该病例主要主诉长期流涕和间歇性头痛,无眼眶症状和其他神经体征。这显示了真菌性鼻窦炎的表现,以及对儿科患者的AFRS进行积极的药物和手术干预的必要性。

结论

总之,尽管AFRS被归类为良性、非侵袭性疾病,但其表现范围可从单纯鼻塞到眶内和/或颅内并发症的体征和症状;儿科病例病情非常严重。需要进行仔细的临床评估、详细的组织病理学检查、导航辅助的鼻内镜鼻窦手术,随后进行类固醇治疗,并进行终身随访以处理复发问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a689/7522375/c21274c7cb60/gr1.jpg

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