Department of Urology, Union Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, China.
Department of Urology, Union Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, China.
Transplant Proc. 2021 Apr;53(3):828-832. doi: 10.1016/j.transproceed.2020.08.035. Epub 2020 Sep 28.
Iliac atherosclerosis is common in renal transplant recipients. In severe cases, it affects intraoperative renal arterial anastomosis and increases the risk of postanastomosis complications. At present, safe and efficient vascular replacement methods are relatively limited. In the 2 renal transplant cases at our center, described here, the donors' iliac arteries were unavailable. We therefore attempted to replace the recipients' diseased external iliac artery with the donors' inferior vena cava and then performed an end-to-side grafting with the attachment in arterial reconstruction. One patient received a single kidney transplantation, while the other received a dual kidney transplantation. Antiplatelet/anticoagulation drug application was avoided, and both patients were observed for more than 6 months. Stable renal graft function was achieved without any vascular complications. During this study, all procedures were in compliance with the Helsinki Congress and the Declaration of Istanbul. For end-stage renal disease patients with severe iliac atherosclerosis who are waiting for kidney transplantation, a donor's vena cava graft could potentially be a promising replacement option to restore external iliac artery patency and reconstruct renal blood flow, without the necessity of harvesting a recipient's autologous vessels or looking for costly artificial ones.
髂动脉粥样硬化在肾移植受者中很常见。在严重的情况下,它会影响术中肾动脉吻合,增加吻合后并发症的风险。目前,安全有效的血管替代方法相对有限。在我们中心的 2 例肾移植病例中,供体的髂动脉无法使用。因此,我们尝试用供体的下腔静脉替换受者患病的髂外动脉,然后在动脉重建中进行端侧吻合。1 例患者接受了单肾移植,另 1 例接受了双肾移植。避免了抗血小板/抗凝药物的应用,两名患者均观察了 6 个月以上。未发生任何血管并发症,移植肾功能稳定。在这项研究中,所有程序均符合赫尔辛基大会和伊斯坦布尔宣言的规定。对于等待肾移植的髂动脉粥样硬化严重的终末期肾病患者,供体的腔静脉移植物可能是一种有前途的替代选择,可以恢复髂外动脉通畅性并重建肾血流,而无需采集受者的自体血管或寻找昂贵的人工血管。