Kupferschmidt H G, Beltzner B E, Schröder K
Angew Parasitol. 1987 Mar;28(1):3-5.
Expanding drug-resistance of P. falciparum strains is one of the main problems of the control and treatment of malignant tropical malaria. The World Health Organisation recommends the in vivo test as well as macro and micro in vitro tests for the epidemiological and clinical diagnosis. The authors describe the methodology of these tests, which helped them to identify the first chloroquine-resistant P. falciparum strains from Moçambique and Angola as well as one fansidar-resistant strain from Angola.
恶性疟原虫菌株耐药性的不断扩大是热带恶性疟疾控制和治疗的主要问题之一。世界卫生组织推荐进行体内试验以及宏观和微观体外试验用于流行病学和临床诊断。作者描述了这些试验的方法,这些方法帮助他们从莫桑比克和安哥拉鉴定出首批耐氯喹的恶性疟原虫菌株,以及从安哥拉鉴定出一株耐 Fansidar 的菌株。