Smith G P, Gibbs J
Ann N Y Acad Sci. 1987;499:132-6. doi: 10.1111/j.1749-6632.1987.tb36204.x.
A number of peptides synthesized and secreted by gastrointestinal cells have been shown to possess significant effects on food intake and on perceptions of hunger and satiety in humans. In this paper, we review the available literature on these effects and emphasize the current obstacles for the therapeutic application of peptides to the problem of obesity.
胃肠道细胞合成并分泌的多种肽已被证明对人类的食物摄入量以及饥饿和饱腹感的感知具有显著影响。在本文中,我们综述了有关这些影响的现有文献,并强调了将肽用于治疗肥胖问题目前所面临的障碍。