Lima Jeruza Mara de Oliveira, Lobo Raquel Uchoa, Rodrigues Deyvison Henrique da Silva, Viana Antônio Brazil, Silva Ricardo Pereira
Medical School of the Federal University of Ceará, Fortaleza, Brasil.
J Hum Hypertens. 2020 Dec;34(12):814-817. doi: 10.1038/s41371-020-00418-y. Epub 2020 Oct 1.
The latest Brazilian Guidelines on ambulatory blood pressure monitoring (ABPM) consider an exam as a useful tool during pregnancy, especially during the first half of pregnancy. They also indicate that white coat hypertension as well as masked hypertension may occur in up to one-third of pregnancies. As white coat hypertension has a more favorable diagnosis than gestational hypertension, it remains associated with 50% of pregnancies and is not associated with complications. Elsewhere, 40% of pregnant women develop gestational hypertension. As per the guidelines, the guidance values should be the same for the general population. The aim of this study was to verify the blood pressure behavior after birth in pregnant women who underwent ABPM and whether ABPM in pregnant women may serve as a predictor of preeclampsia and abnormalities in newborns. Between 01 January 2017 and 31 December 2019, 117 ABPM routines in pregnant women were performed at Unicordis. Among them, 40 were requested for the diagnosis of hypertension, and 77 were requested for antihypertensive therapeutic assessment. The study population comprised pregnant women who underwent ABPM for the diagnosis of hypertension. We assessed a population that comprised 31 subjects who underwent ABPM, 17 of whom had normal results and 14 of whom had abnormal results. Of the 14 pregnant women with abnormal blood pressure behavior, only three (21%) had a physiological drop in blood pressure, seven had attenuated descent, and four did not have blood arterial descent. The age of the pregnant women ranged from 21 to 42 years. The gestational age at the beginning of ABPM ranged from 6 to 37 weeks. In the group with normal ABPM, two pregnant women (11.7%) developed preeclampsia during pregnancy. Additionally, in the group with abnormal ABPM, seven pregnant women (50%) developed preeclampsia during pregnancy. In the group with normal ABPM, three newborns had abnormalities (17.6%); in the group with abnormal ABPM, four newborns had abnormalities (28.5%). In the group with normal ABPM, two subjects developed hypertension after birth (11.7%). In the group with abnormal ABPM, ten subjects (71%) remained hypertensive following birth (Table 1). Conclusions: (1) the results show that the proportion of patients who presented with preeclampsia was higher among individuals with abnormal ABPM than that among individuals with normal ABPM. (2) The proportion of subjects with hypertension following birth was higher among individuals with abnormal ABPM than that among individuals with normal ABPM.
最新的巴西动态血压监测(ABPM)指南认为,该检查在孕期是一种有用的工具,尤其是在妊娠前半期。指南还指出,高达三分之一的孕妇可能会出现白大衣高血压以及隐匿性高血压。由于白大衣高血压的诊断比妊娠期高血压更有利,它仍与50%的妊娠相关,且与并发症无关。在其他情况中,40%的孕妇会出现妊娠期高血压。根据该指南,一般人群的指导值应相同。本研究的目的是验证接受ABPM的孕妇产后的血压情况,以及孕妇的ABPM是否可作为子痫前期和新生儿异常的预测指标。2017年1月1日至2019年12月31日期间,Unicordis对117名孕妇进行了ABPM检查。其中,40例是为了诊断高血压而进行检查,77例是为了进行降压治疗评估。研究人群包括接受ABPM以诊断高血压的孕妇。我们评估了31名接受ABPM检查的受试者,其中17名结果正常,14名结果异常。在14名血压行为异常的孕妇中,只有3名(21%)血压有生理性下降,7名下降减弱,4名没有动脉血压下降。孕妇年龄在21至42岁之间。ABPM开始时的孕周在6至37周之间。在ABPM结果正常的组中,有2名孕妇(11.7%)在孕期发生了子痫前期。此外,在ABPM结果异常的组中,有7名孕妇(50%)在孕期发生了子痫前期。在ABPM结果正常的组中,有3名新生儿有异常(17.6%);在ABPM结果异常的组中,有4名新生儿有异常(28.5%)。在ABPM结果正常的组中,有2名受试者产后发生了高血压(11.7%)。在ABPM结果异常的组中,有10名受试者(71%)产后仍患有高血压(表1)。结论:(1)结果表明,ABPM结果异常的患者发生子痫前期的比例高于ABPM结果正常的患者。(2)ABPM结果异常的患者产后患高血压的比例高于ABPM结果正常的患者。