Cleveland Clinic Lerner College of Medicine, Cleveland, OH.
Department of Obstetrics and Gynecology, MetroHealth Medical Center, Cleveland, OH.
Yale J Biol Med. 2020 Sep 30;93(4):587-592. eCollection 2020 Sep.
Over the last few years, research teams have made significant advancements in treating absolute uterine factor infertility through uterus transplantation, culminating in the birth of the first US baby born from a uterus transplant in November 2017. However, studies have differed on the choice of either deceased or living donors, with some centers even exploring both methods. As researchers continue to investigate the medical feasibility of these approaches, it is also important for the medical community to consider how deceased and living uterus donation differ ethically. We argue that if living and deceased donation demonstrate equivalent clinical efficacy and the deceased donor pool is sufficient, living uterus donation should be reevaluated and may no longer be ethically justifiable.
在过去的几年中，研究团队在通过子宫移植治疗绝对子宫因素不孕方面取得了重大进展，最终于 2017 年 11 月诞生了首例美国子宫移植婴儿。然而，关于是选择已故供体还是活体供体，研究结果存在差异，一些中心甚至同时探索这两种方法。随着研究人员继续研究这些方法的医学可行性，医学界也有必要考虑活体和已故供体捐赠在伦理方面的差异。我们认为，如果活体和已故供体捐赠在临床效果上相当，且已故供体资源充足，那么应该重新评估活体子宫捐赠，并且可能不再具有伦理合理性。
