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无肝硬化情况下出现复发性出血的造口旁静脉曲张

Parastomal Varices with Recurrent Bleeding in the Absence of Liver Cirrhosis.

作者信息

Kopel Jonathan, Baucom Rebeccah, Campbell Samuel, Brower Gregory L

机构信息

Texas Tech University Health Sciences Center School of Medicine, Lubbock, TX, USA.

Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, TX, USA.

出版信息

Case Rep Gastrointest Med. 2020 Sep 14;2020:2653848. doi: 10.1155/2020/2653848. eCollection 2020.

Abstract

Gastrointestinal (GI) bleeding is a common problem in patients with portal hypertension. One of the most common causes of GI bleeding are varices (e.g., esophageal varices). In some instances, varices can develop between an intestinal stoma and the abdominal wall vasculature, known as parastomal varices. Specifically, parastomal varices are common in patients with a preexisting stoma and concurrent chronic portal hypertension. These patients often present with recurrent bleeding and may require regular transfusions. Herein, we report on a patient with parastomal varices and portal hypertension without hepatic cirrhosis. Given the high morbidity and mortality associated with surgical interventions, most clinical guidelines encourage observation and medical management of bleeding from parastomal varices. Among the nonsurgical interventions, manual compression and local maneuvers often successfully stop the bleeding. However, subsequent rebleeding from parastomal varices can remain a problem requiring additional treatment. Further research is needed to investigate appropriate medical or surgical alternatives for managing parastomal varices bleeding.

摘要

胃肠道(GI)出血是门静脉高压患者的常见问题。胃肠道出血最常见的原因之一是静脉曲张(如食管静脉曲张)。在某些情况下,静脉曲张可在肠造口与腹壁血管系统之间形成,称为造口旁静脉曲张。具体而言,造口旁静脉曲张在已有造口且并发慢性门静脉高压的患者中很常见。这些患者常出现反复出血,可能需要定期输血。在此,我们报告一例无肝硬化的造口旁静脉曲张和门静脉高压患者。鉴于手术干预相关的高发病率和死亡率,大多数临床指南鼓励对造口旁静脉曲张出血进行观察和药物治疗。在非手术干预中,手法压迫和局部操作通常能成功止血。然而,造口旁静脉曲张随后的再出血可能仍然是一个需要进一步治疗的问题。需要进一步研究以探讨治疗造口旁静脉曲张出血的合适药物或手术替代方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd3c/7509571/765f5c03ff7c/CRIGM2020-2653848.001.jpg

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