Wakabayashi T, Yoshida J, Ishiyama J, Kageyama N
Gan To Kagaku Ryoho. 1987 Jul;14(7):2374-7.
Combination chemotherapy of Cis-platinum with Aclarubicin was performed in patients with intracranial alveolar rhabdomyosarcoma. These patients were treated with Cis-platinum (20 mg/day) and Aclarubicin (20 mg/day) for 5 days. After two trials with about a four-week interval, complete tumor regression on CT scan was observed. Mild gastrointestinal toxicity was observed in these patients but the symptoms were transient and soon disappeared. No other side effects appeared, on or after treatment. This result demonstrated that combination chemotherapy of Cis-platinum and Aclarubicin is an effective regimen for remission induction chemotherapy in patients with intracranial sarcoma.
对颅内肺泡横纹肌肉瘤患者进行了顺铂与阿柔比星的联合化疗。这些患者接受顺铂（20毫克/天）和阿柔比星（20毫克/天）治疗，持续5天。经过两次间隔约四周的试验后，CT扫描显示肿瘤完全消退。这些患者出现了轻度胃肠道毒性，但症状是短暂的，很快就消失了。治疗期间及治疗后未出现其他副作用。这一结果表明，顺铂和阿柔比星联合化疗是颅内肉瘤患者诱导缓解化疗的有效方案。
