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减肥手术期间同时进行食管裂孔疝修补术:加固会产生差异吗?

Concomitant hiatal hernia repair during bariatric surgery: does the reinforcement make the difference?

作者信息

Boru Cristian E, Termine Pietro, Antypas Pavlos, Iossa Angelo, Ciccioriccio Chiara M, DE Angelis Francesco, Micalizzi Alessandra, Silecchia Gianfranco

机构信息

Division of General Surgery and Bariatric Center of Excellence-IFSO EC, Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy -

Division of General Surgery and Bariatric Center of Excellence-IFSO EC, Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy.

出版信息

Minerva Surg. 2021 Feb;76(1):33-42. doi: 10.23736/S2724-5691.20.08503-X. Epub 2020 Oct 2.

Abstract

BACKGROUND

Hiatal hernia repair (HHR) is still controversial during bariatric procedures, especially in case of laparoscopic sleeve gastrectomy (LSG).

AIMS

to report the long-term results of concomitant HHR, evaluating the safety and efficacy of posterior cruroplasty (PC), simple or reinforced with biosynthetic, absorbable Bio-A mesh (Gore, Flagstaff, AZ, USA). Primary endpoint: PC's failure, defined as symptomatic HH recurrence, nonresponding to medical treatment and requiring revisional surgery.

METHODS

The prospective database of 1876 bariatric operations performed in a center of excellence between 2011-2019 was searched for concomitant HHR. Intraoperative measurement of the hiatal surface area (HSA) was performed routinely.

RESULTS

A total of 250 patients undergone bariatric surgery and concomitant HHR (13%). Simple PC (group A, 151 patients) was performed during 130 LSG, 5 re-sleeves and 16 gastric bypasses; mean BMI 43.4±5.8 kg/m, HSA mean size 3.4±2 cm. Reinforced PC (group B) was performed in 99 cases: 62 primary LSG, 22 LGB and 15 revisions of LSG; mean BMI 44.6±7.7 kg/m2, HSA mean size 6.7±2 cm. PC's failure, with intrathoracic migration (ITM) of the LSG was encountered in 12 cases (8%) of simple vs. only 4 cases (4%) of reinforced PC (P=0.23); hence, a repeat, reinforced PC and R-en-Y gastric bypass (LRYGB) was performed laparoscopically in all cases. No mesh-related complications were registered perioperatively or after long-term follow-up (mean 50 months). One case of cardiac metaplasia without goblet cells was detected 4 years postoperatively; conversion to LRYGB, with reinforced redo of the PC was performed. The Cox hazard analysis showed that the use of more than four stitches for cruroplasty represents a negative factor on recurrence (HR=8; P<0.05).

CONCLUSIONS

An aggressive search for and repair of HH during any bariatric procedure seems advisable, allowing a low HH recurrence rates. Additional measures, like mesh reinforcement of crural closure with biosynthetic, absorbable mesh, seem to improve results on long term follow-up, especially in case of larger hiatal defects. In our experience, reinforcement of even smaller defects seems advisable in obese population.

摘要

背景

在减重手术过程中,食管裂孔疝修补术(HHR)仍存在争议,尤其是在腹腔镜袖状胃切除术(LSG)的情况下。

目的

报告同期进行HHR的长期结果,评估单纯或用生物合成可吸收生物A网片(美国亚利桑那州弗拉格斯塔夫戈尔公司生产)加强的后十字韧带成形术(PC)的安全性和有效性。主要终点:PC失败,定义为有症状的HH复发,药物治疗无效且需要再次手术。

方法

在一个卓越中心2011年至2019年期间进行的1876例减重手术的前瞻性数据库中搜索同期进行的HHR。常规进行术中食管裂孔表面积(HSA)测量。

结果

共有250例患者接受了减重手术并同期进行了HHR(13%)。在130例LSG、5例再次袖状胃切除术和16例胃旁路手术中进行了单纯PC(A组,151例患者);平均BMI为43.4±5.8kg/m²,HSA平均大小为3.4±2cm²。99例进行了加强PC(B组):62例初次LSG、22例腹腔镜胃旁路术(LGB)和15例LSG翻修术;平均BMI为44.6±7.7kg/m²,HSA平均大小为6.7±2cm²。单纯PC组有12例(8%)出现PC失败,伴有LSG的胸腔内移位(ITM),而加强PC组仅4例(4%)(P=0.23);因此,所有病例均通过腹腔镜进行了再次加强PC和R-Y胃旁路术(LRYGB)。围手术期或长期随访(平均50个月)均未记录到与网片相关的并发症。术后4年检测到1例无杯状细胞的贲门化生;进行了转为LRYGB并加强重做PC的手术。Cox风险分析表明,十字韧带成形术使用超过4针是复发的负面因素(HR=8;P<0.05)。

结论

在任何减重手术过程中积极寻找并修复HH似乎是可取的,可使HH复发率较低。额外的措施,如用生物合成可吸收网片加强裂孔闭合,在长期随访中似乎能改善结果,尤其是在食管裂孔缺损较大的情况下。根据我们的经验,在肥胖人群中,即使是较小的缺损加强修复似乎也是可取的。

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