Boru Cristian E, Termine Pietro, Antypas Pavlos, Iossa Angelo, Ciccioriccio Chiara M, DE Angelis Francesco, Micalizzi Alessandra, Silecchia Gianfranco
Division of General Surgery and Bariatric Center of Excellence-IFSO EC, Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy -
Division of General Surgery and Bariatric Center of Excellence-IFSO EC, Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy.
Minerva Surg. 2021 Feb;76(1):33-42. doi: 10.23736/S2724-5691.20.08503-X. Epub 2020 Oct 2.
Hiatal hernia repair (HHR) is still controversial during bariatric procedures, especially in case of laparoscopic sleeve gastrectomy (LSG).
to report the long-term results of concomitant HHR, evaluating the safety and efficacy of posterior cruroplasty (PC), simple or reinforced with biosynthetic, absorbable Bio-A mesh (Gore, Flagstaff, AZ, USA). Primary endpoint: PC's failure, defined as symptomatic HH recurrence, nonresponding to medical treatment and requiring revisional surgery.
The prospective database of 1876 bariatric operations performed in a center of excellence between 2011-2019 was searched for concomitant HHR. Intraoperative measurement of the hiatal surface area (HSA) was performed routinely.
A total of 250 patients undergone bariatric surgery and concomitant HHR (13%). Simple PC (group A, 151 patients) was performed during 130 LSG, 5 re-sleeves and 16 gastric bypasses; mean BMI 43.4±5.8 kg/m, HSA mean size 3.4±2 cm. Reinforced PC (group B) was performed in 99 cases: 62 primary LSG, 22 LGB and 15 revisions of LSG; mean BMI 44.6±7.7 kg/m2, HSA mean size 6.7±2 cm. PC's failure, with intrathoracic migration (ITM) of the LSG was encountered in 12 cases (8%) of simple vs. only 4 cases (4%) of reinforced PC (P=0.23); hence, a repeat, reinforced PC and R-en-Y gastric bypass (LRYGB) was performed laparoscopically in all cases. No mesh-related complications were registered perioperatively or after long-term follow-up (mean 50 months). One case of cardiac metaplasia without goblet cells was detected 4 years postoperatively; conversion to LRYGB, with reinforced redo of the PC was performed. The Cox hazard analysis showed that the use of more than four stitches for cruroplasty represents a negative factor on recurrence (HR=8; P<0.05).
An aggressive search for and repair of HH during any bariatric procedure seems advisable, allowing a low HH recurrence rates. Additional measures, like mesh reinforcement of crural closure with biosynthetic, absorbable mesh, seem to improve results on long term follow-up, especially in case of larger hiatal defects. In our experience, reinforcement of even smaller defects seems advisable in obese population.
在减重手术过程中,食管裂孔疝修补术(HHR)仍存在争议,尤其是在腹腔镜袖状胃切除术(LSG)的情况下。
报告同期进行HHR的长期结果,评估单纯或用生物合成可吸收生物A网片(美国亚利桑那州弗拉格斯塔夫戈尔公司生产)加强的后十字韧带成形术(PC)的安全性和有效性。主要终点:PC失败,定义为有症状的HH复发,药物治疗无效且需要再次手术。
在一个卓越中心2011年至2019年期间进行的1876例减重手术的前瞻性数据库中搜索同期进行的HHR。常规进行术中食管裂孔表面积(HSA)测量。
共有250例患者接受了减重手术并同期进行了HHR(13%)。在130例LSG、5例再次袖状胃切除术和16例胃旁路手术中进行了单纯PC(A组,151例患者);平均BMI为43.4±5.8kg/m²,HSA平均大小为3.4±2cm²。99例进行了加强PC(B组):62例初次LSG、22例腹腔镜胃旁路术(LGB)和15例LSG翻修术;平均BMI为44.6±7.7kg/m²,HSA平均大小为6.7±2cm²。单纯PC组有12例(8%)出现PC失败,伴有LSG的胸腔内移位(ITM),而加强PC组仅4例(4%)(P=0.23);因此,所有病例均通过腹腔镜进行了再次加强PC和R-Y胃旁路术(LRYGB)。围手术期或长期随访(平均50个月)均未记录到与网片相关的并发症。术后4年检测到1例无杯状细胞的贲门化生;进行了转为LRYGB并加强重做PC的手术。Cox风险分析表明,十字韧带成形术使用超过4针是复发的负面因素(HR=8;P<0.05)。
在任何减重手术过程中积极寻找并修复HH似乎是可取的,可使HH复发率较低。额外的措施,如用生物合成可吸收网片加强裂孔闭合,在长期随访中似乎能改善结果,尤其是在食管裂孔缺损较大的情况下。根据我们的经验,在肥胖人群中,即使是较小的缺损加强修复似乎也是可取的。