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[免疫酶检测系统在确定肌红蛋白、纤维蛋白原、纤维蛋白 - 纤维蛋白原降解产物和纤连蛋白水平用于躯体疾病诊断中的应用可能性]

[Possibilities of using immunoenzyme test systems for determining levels of myoglobin, fibrinogen, fibrin-fibrinogen degradation products and fibronectin in the diagnosis of somatic diseases].

作者信息

Ermolin G A, Shelepova T M, Dikov M M, Osmanov S K, Voloshchuk O M

出版信息

Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1987;10(1):33-7.

PMID:3300700
Abstract

Clinical trials of immunoenzyme test-systems for the quantitative determination of fibronectin, fibrinogen, fibrin/fibrinogen degradation products and myoglobin have been performed on serum and plasma samples obtained from patients and healthy donors. The tests were informative and possessed diagnostic value in the following conditions: fibronectin--in pyogenic septic complications of newborns, burn infections; fibrinogen and fibrin/fibrinogen products--in thrombosis, myocardial infarction and disseminated intravascular coagulation syndrome; myoglobin--in myocardial infarction.

摘要

已对从患者和健康供体获取的血清和血浆样本进行了免疫酶检测系统的临床试验,以定量测定纤连蛋白、纤维蛋白原、纤维蛋白/纤维蛋白原降解产物和肌红蛋白。这些检测在以下情况下具有信息价值和诊断价值:纤连蛋白——在新生儿化脓性败血症并发症、烧伤感染中;纤维蛋白原和纤维蛋白/纤维蛋白原产物——在血栓形成、心肌梗死和弥散性血管内凝血综合征中;肌红蛋白——在心肌梗死中。

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[Clinical evaluation of a test for plasma fibrin/fibrinogen degradation products (FDP) based on monoclonal anti-FDP antibody technology: an application for the scoring system of the disseminated intravascular coagulation (DIC) diagnostic criteria].基于单克隆抗纤维蛋白/纤维蛋白原降解产物(FDP)抗体技术的血浆FDP检测的临床评估:在弥散性血管内凝血(DIC)诊断标准评分系统中的应用
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