Velagic Vedran, Prepolec Ivan, Pasara Vedran, Puljevic Mislav, Puljevic Davor, Planinc Ivo, Samardzic Jure, Milicic Davor
University of Zagreb School of Medicine, Department of Cardiovascular Diseases, University Hospital Centre Zagreb, Zagreb, Croatia.
University of Zagreb School of Medicine, Department of Cardiovascular Diseases, University Hospital Centre Zagreb, Zagreb, Croatia.
Indian Pacing Electrophysiol J. 2020 Nov-Dec;20(6):273-280. doi: 10.1016/j.ipej.2020.09.003. Epub 2020 Sep 30.
To examine the learning curves of atrial fibrillation (AF) ablation comparing the cryoballoon (CB) and radiofrequency (RF) catheters.
We performed a retrospective data analysis from the initiation of AF ablation program in our center. For CB ablation, a second generation 28 mm balloon was utilized and for RF ablation.
A total of 100 consecutive patients (50 in each group) have been enrolled in the study (male 74%, mean age 58.9 ± 10 years, paroxysmal AF 85%). The mean procedure time was shorter for CB (116.6 ± 39.8 min) than RF group (191.8 ± 101.1 min) (p < 0.001). There was no difference in the mean fluoroscopy time, 24.2 ± 10.6 min in RF and 22.4 ± 11.7 min in CB group, (p = 0.422). Seven major complications occurred during the study; 5 in RF group (10%) and 2 in CB group (4%) (p = 0.436). After the mean follow up of 14.5 ± 2.4 months, 15 patients in RF group (30%) and 11 in CB group (26%) experienced AF recurrences (P = 0.300).
When starting a new AF ablation program, our results suggest that CB significantly shortens procedure while fluoroscopy time and clinical outcomes are comparable to RF ablation.
比较冷冻球囊(CB)和射频(RF)导管在心房颤动(AF)消融中的学习曲线。
我们对本中心启动AF消融项目以来的数据进行了回顾性分析。CB消融采用第二代28mm球囊,RF消融采用[此处原文未提及RF消融具体使用的设备,翻译时保留原文格式]。
共有100例连续患者(每组50例)纳入本研究(男性占74%,平均年龄58.9±10岁,阵发性AF占85%)。CB组的平均手术时间(116.6±39.8分钟)短于RF组(191.8±101.1分钟)(p<0.001)。两组的平均透视时间无差异,RF组为24.2±10.6分钟,CB组为22.4±11.7分钟(p = 0.422)。研究期间发生了7例主要并发症;RF组5例(10%),CB组2例(4%)(p = 0.436)。平均随访14.5±2.4个月后,RF组有15例患者(30%)发生AF复发,CB组有11例患者(26%)发生AF复发(P = 0.300)。
在启动新的AF消融项目时,我们的结果表明,CB显著缩短了手术时间,而透视时间和临床结果与RF消融相当。