Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d'Orleans II, Viale delle Scienze-Bd. 16-17, 90128 Palermo, Italy.
Molecules. 2020 Sep 30;25(19):4487. doi: 10.3390/molecules25194487.
Two mononuclear Pd(II) complexes [PdCl(pfptp)] () and [PdCl(pfhtp)] (), with ligands 2-(3-perfluoropropyl-1-methyl-1,2,4-triazole-5yl)-pyridine () and 2-(3-perfluoroheptyl-1-methyl-1,2,4-triazole-5yl)-pyridine (), were synthesized and structurally characterized. The two complexes showed a bidentate coordination of the ligand occurring through N atom of pyridine ring and N4 atom of 1,2,4-triazole. Both complexes showed antimicrobial activity when tested against both Gram-negative and Gram-positive bacterial strains.
合成并结构表征了两个单核 Pd(II) 配合物PdCl(pfptp)和PdCl(pfhtp),配体为 2-(3-全氟丙基-1-甲基-1,2,4-三唑-5-基)-吡啶()和 2-(3-全氟庚基-1-甲基-1,2,4-三唑-5-基)-吡啶()。这两个配合物表现出配体通过吡啶环的 N 原子和 1,2,4-三唑的 N4 原子的双齿配位。当测试对革兰氏阴性和革兰氏阳性细菌菌株的抗菌活性时,两个配合物都表现出抗菌活性。