Sisli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, Eye Clinic, İstanbul, Turkey.
Bursa Retina Eye Hospital, Bursa, Turkey.
Eur J Ophthalmol. 2021 Mar;31(2):766-773. doi: 10.1177/1120672120962041. Epub 2020 Oct 2.
To present clinical ocular manifestations, radiological features and surgical results of giant paranasal osteomas involving the orbit.
Retrospective, interventional, case series.
The study included patients treated for giant paranasal osteoma involving the orbit. Total or subtotal excision of the tumor was performed via external approach. Clinical characteristics including presenting symptoms, radiologic investigation, histopathology and details of the surgery were recorded.
Of the six patients included; four were male and two were female. Mean age was 46.8 years (range 12-70 years). Five patients had unilateral, one patient had bileteral disease. The presenting complaints included complete ( = 2/6) or partial ( = 4/6) limitation of eye movements depending on the location and size of the tumor, diplopia ( = 5/6), vision loss ( = 2/6) exophthalmos ( = 6/6) and reduced pupillary light reflex ( = 2/6). The presumed origin of the tumor was frontoethmoidal region ( = 2/6), frontal sinus ( = 3/6) and ethmoid sinus ( = 1/6). Total resection was achieved in three of the patients whereas partial resection was achieved in remaining three patients due to risk of incremental neurological damage. Mild ptosis was observed in all patients during the postoperative period (temporary, = 4; permanent, = 2).
Despite the benign nature of osteomas, severe functional impairment including vision loss due to compression of the optic nerve and diplopia might occur in case of orbital involvement. Osteomas with an orbital extension > %50 of the bony orbit volume are more prone to cause irreversible visual loss. Surgical resection is still the mainstay of therapy.
介绍累及眼眶的巨大副鼻窦骨瘤的临床眼部表现、影像学特征和手术结果。
回顾性、干预性、病例系列研究。
本研究纳入了接受累及眼眶的巨大副鼻窦骨瘤治疗的患者。通过外路进行肿瘤的全部或部分切除术。记录了临床特征,包括主要症状、影像学检查、组织病理学和手术细节。
纳入的 6 例患者中,男性 4 例,女性 2 例。平均年龄为 46.8 岁(范围 12-70 岁)。5 例为单侧,1 例为双侧病变。主要症状包括眼球运动受限(完全,2/6;部分,4/6),复视(5/6),视力下降(2/6),眼球突出(6/6)和瞳孔光反射减弱(2/6)。肿瘤的推测起源为额窦(2/6)、额窦(3/6)和筛窦(1/6)。3 例患者实现了完全切除,而其余 3 例患者由于存在渐进性神经损伤的风险而仅实现了部分切除。所有患者术后均出现轻度上睑下垂(暂时性,4 例;永久性,2 例)。
尽管骨瘤为良性肿瘤,但累及眼眶时可因视神经受压和复视而导致严重的功能障碍,甚至视力丧失。眼眶受累超过骨眶容积的 50%的骨瘤更易导致不可逆转的视力丧失。手术切除仍然是主要的治疗方法。