Department of Neurology, Far Eastern Memorial Hospital, New Taipei, Taiwan; Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan.
Living Water Neurological Clinic, Tainan, Taiwan.
Prog Brain Res. 2020;255:1-27. doi: 10.1016/bs.pbr.2020.05.017. Epub 2020 Jun 12.
Migraine is a prevalent disorder with high disability and socioeconomic costs. Preventive treatment has been shown to decrease headache frequency, improve quality of life and minimize the medical expenses. Although many medications have been proved effective, they are underutilized. For the past several years, significant progress has been made with the emerging options of calcitonin-gene related peptide (CGRP) monoclonal antibodies and antagonists. The choices of these medications depend on not only the evidences of effects and possible side effects of the medications but also comorbidities, preferences and even special considerations of the individual patient such as breast feeding and reproduction.
偏头痛是一种常见疾病，具有较高的残疾和社会经济成本。预防治疗已被证明可以减少头痛发作频率、改善生活质量和最小化医疗费用。尽管有许多药物已被证明有效，但它们的利用率较低。在过去的几年中，随着降钙素基因相关肽（CGRP）单克隆抗体和拮抗剂等新兴选择的出现，取得了重大进展。这些药物的选择不仅取决于药物的疗效和可能的副作用的证据，还取决于合并症、患者的偏好，甚至是个体患者的特殊考虑因素，如母乳喂养和生殖。
