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1
Azithromycin may increase hematologic relapse rates in matched unrelated donor hematopoietic cell transplant recipients who receive anti-thymocyte globulin, but not in most other recipients.阿奇霉素可能会增加接受抗胸腺细胞球蛋白的匹配无关供体造血细胞移植受者的血液学复发率，但在大多数其他受者中则不会。
Bone Marrow Transplant. 2021 Mar;56(3):745-748. doi: 10.1038/s41409-020-01073-0. Epub 2020 Oct 2.
2
Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy.性别不匹配的造血细胞移植的风险和益处因预处理策略而异。
Haematologica. 2015 Nov;100(11):1477-85. doi: 10.3324/haematol.2015.125294. Epub 2015 Aug 6.
3
Unrelated Donor Transplant Recipients Given Thymoglobuline Have Superior GRFS When Compared to Matched Related Donor Recipients Undergoing Transplantation without ATG.与未用 ATG 的匹配相关供者移植受者相比，接受胸腺球蛋白的无关供者移植受者具有更好的 GRFS。
Biol Blood Marrow Transplant. 2020 Oct;26(10):1868-1875. doi: 10.1016/j.bbmt.2020.06.030. Epub 2020 Jul 5.
4
Addition of anti-thymocyte globulin to standard graft-versus-host disease prophylaxis versus standard treatment alone in patients with haematological malignancies undergoing transplantation from unrelated donors: final analysis of a randomised, open-label, multicentre, phase 3 trial.在接受无关供体移植的血液系统恶性肿瘤患者中，在标准移植物抗宿主病预防方案基础上加用抗胸腺细胞球蛋白与单纯标准治疗的对比：一项随机、开放标签、多中心3期试验的最终分析。
Lancet Haematol. 2020 Feb;7(2):e100-e111. doi: 10.1016/S2352-3026(19)30220-0. Epub 2020 Jan 17.
5
The Role of Low-dose Anti-thymocyte Globulin as Standard Prophylaxis in Mismatched and Matched Unrelated Hematopoietic Peripheral Stem Cell Transplantation for Hematologic Malignancies.低剂量抗胸腺细胞球蛋白在血液系统恶性肿瘤不匹配及匹配的非亲缘造血外周血干细胞移植中作为标准预防措施的作用
Clin Lymphoma Myeloma Leuk. 2017 Oct;17(10):658-666. doi: 10.1016/j.clml.2017.06.008. Epub 2017 Jun 29.
6
Reduced intensity haplo plus single cord transplant compared to double cord transplant: improved engraftment and graft-versus-host disease-free, relapse-free survival.与双脐带移植相比，减低强度单倍体加单脐带移植：植入改善，无移植物抗宿主病，无复发生存率提高。
Haematologica. 2016 May;101(5):634-43. doi: 10.3324/haematol.2015.138594. Epub 2016 Feb 11.
7
Does Lymphocyte Count Impact Dosing of Anti-Thymocyte Globulin in Unrelated Donor Stem Cell Transplantation?淋巴细胞计数会影响无关供体干细胞移植中抗胸腺细胞球蛋白的剂量吗？
Biol Blood Marrow Transplant. 2020 Jul;26(7):1298-1302. doi: 10.1016/j.bbmt.2020.02.026. Epub 2020 Mar 9.
8
Anti-thymocyte globulin as graft-versus-host disease prevention in the setting of allogeneic peripheral blood stem cell transplantation: a review from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.抗胸腺细胞球蛋白在异基因外周血干细胞移植中预防移植物抗宿主病：欧洲血液与骨髓移植学会急性白血病工作组的综述
Haematologica. 2017 Feb;102(2):224-234. doi: 10.3324/haematol.2016.148510. Epub 2016 Dec 7.
9
Impact of Donor and Recipient Cytomegalovirus Serostatus on Outcomes of Antithymocyte Globulin-Conditioned Hematopoietic Cell Transplantation.供体和受体巨细胞病毒血清学状态对抗胸腺细胞球蛋白预处理的造血细胞移植结局的影响
Biol Blood Marrow Transplant. 2016 Sep;22(9):1654-1663. doi: 10.1016/j.bbmt.2016.05.020. Epub 2016 May 28.
10
Donor-Recipient Matching for KIR Genotypes Reduces Chronic GVHD and Missing Inhibitory KIR Ligands Protect against Relapse after Myeloablative, HLA Matched Hematopoietic Cell Transplantation.KIR基因型的供受者匹配可减少慢性移植物抗宿主病，且缺乏抑制性KIR配体可预防清髓性、HLA匹配的造血细胞移植后的复发。
PLoS One. 2016 Jun 24;11(6):e0158242. doi: 10.1371/journal.pone.0158242. eCollection 2016.

引用本文的文献

1
Airway disease in hematologic malignancies.血液恶性肿瘤中的气道疾病。
Expert Rev Respir Med. 2022 Mar;16(3):303-313. doi: 10.1080/17476348.2022.2043746. Epub 2022 Feb 21.
2
The pulmonary metatranscriptome prior to pediatric HCT identifies post-HCT lung injury.在儿科造血干细胞移植前的肺部宏转录组可识别移植后肺部损伤。
Blood. 2021 Mar 25;137(12):1679-1689. doi: 10.1182/blood.2020009246.

Azithromycin may increase hematologic relapse rates in matched unrelated donor hematopoietic cell transplant recipients who receive anti-thymocyte globulin, but not in most other recipients.

作者信息

Sheshadri Ajay, Saliba Rima, Patel Badar, Ahmed Tahreem, Bueno Luis C, Arain Muhammad H, Mehta Rohtesh S, Popat Uday R, Hosing Chitra M, Rondon Gabriela, Bashoura Lara, Dickey Burton F, Champlin Richard E, Alousi Amin M

机构信息

Departments of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

出版信息

Bone Marrow Transplant. 2021 Mar;56(3):745-748. doi: 10.1038/s41409-020-01073-0. Epub 2020 Oct 2.

DOI:10.1038/s41409-020-01073-0
PMID:33009515
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7987872/
Abstract
摘要