Lottenberg R, Kitchens C S
Cardiovasc Clin. 1987;18(1):3-12.
Our original understanding of coagulation was too simple. The waterfall or cascade system made sense but never gave clues either to points for control of the reaction or to areas to inhibit or reverse clotting. We now know critical points for control and reversal of hemostasis. By understanding more modern physiology, one is better able to design rational treatment programs to negate unwanted thrombosis. This chapter gives the reader a physiologic foundation to underscore the subsequent chapters.
我们最初对凝血的理解过于简单。瀑布式或级联系统有其合理性，但从未为控制反应的关键点或抑制或逆转凝血的区域提供线索。我们现在知道了止血控制和逆转的关键点。通过了解更现代的生理学，人们能够更好地设计合理的治疗方案来消除不必要的血栓形成。本章为读者提供一个生理学基础，以突出后续各章。
