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帕金森病患者的单髁膝关节置换术。

Unicompartmental knee arthroplasty in patients with Parkinson's disease.

作者信息

Goh Graham S, Zeng Gerald Joseph, Thever Yogen, Foong Wei Sheng, Tay Darren Keng-Jin, Lo Ngai-Nung, Yeo Seng-Jin, Liow Ming Han Lincoln

机构信息

Department of Orthopedic Surgery, Singapore General Hospital, Singapore.

Department of Orthopedic Surgery, Singapore General Hospital, Singapore.

出版信息

Knee. 2020 Oct;27(5):1325-1331. doi: 10.1016/j.knee.2020.06.017. Epub 2020 Jul 27.

Abstract

BACKGROUND

Parkinson's disease (PD) adversely affects physical function after joint replacement. The biomechanical advantages of unicompartmental knee arthroplasty (UKA) may be particularly beneficial for these patients who suffer from gait and kinetic abnormalities. We aimed to describe the functional outcomes, complications and survivorship after UKA in patients with PD.

METHODS

Ten patients (11 knees) undergoing primary fixed-bearing UKA for medial osteoarthritis were studied. Knee Society Knee (KSKS) and Function Scores (KSFS), as well as the Short-Form-36 (SF-36) Mental (MCS) and Physical Component Scores (PCS) were assessed preoperatively, at six months and at two years postoperatively. Complications, survivorship and all-cause mortality were analyzed.

RESULTS

No perioperative complications occurred. Length of stay was 5 ± 2 days and no patients were discharged to rehabilitation or readmitted. Nine of 11 knees had a flexion contracture preoperatively and this remained unchanged at two years. KSKS and SF-36 PCS improved significantly. However, there was no improvement in KSFS or SF-36 MCS. All patients achieved minimal clinically important difference for KSKS, six of 11 for KSFS and nine of 11 for SF-36 PCS. At mean 10 ± 5 years, there was one revision for progression of osteoarthritis. Seven of 10 patients progressed in Hoehn and Yahr stage and only three were able to ambulate independently at last follow-up.

CONCLUSIONS

Patients suffering from osteoarthritis and PD can experience a substantial improvement in knee pain with low morbidity after UKA. However, the improved kinematics of UKA did not translate to an improved range of motion or knee function postoperatively.

摘要

背景

帕金森病(PD)对关节置换后的身体功能有不利影响。单髁膝关节置换术(UKA)的生物力学优势可能对这些存在步态和动力学异常的患者特别有益。我们旨在描述PD患者行UKA后的功能结局、并发症和假体生存率。

方法

研究了10例(11膝)因内侧骨关节炎接受初次固定平台UKA的患者。术前、术后6个月和2年评估膝关节协会膝关节(KSKS)和功能评分(KSFS),以及简明健康状况调查量表(SF-36)的心理(MCS)和生理健康评分(PCS)。分析并发症、假体生存率和全因死亡率。

结果

未发生围手术期并发症。住院时间为5±2天,无患者出院后接受康复治疗或再次入院。11膝中有9膝术前存在屈曲挛缩,2年时仍无变化。KSKS和SF-36 PCS显著改善。然而,KSFS或SF-36 MCS无改善。所有患者的KSKS均达到最小临床重要差异,11例中有6例的KSFS和11例中有9例的SF-36 PCS达到最小临床重要差异。平均随访10±5年时,有1例因骨关节炎进展而行翻修手术。10例患者中有7例Hoehn-Yahr分期进展,最后一次随访时只有3例能够独立行走。

结论

骨关节炎合并PD的患者行UKA后膝关节疼痛可显著改善,且发病率低。然而,UKA改善的运动学并未转化为术后改善的活动范围或膝关节功能。

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