Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland.
Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland.
Infect Dis Clin North Am. 2020 Dec;34(4):659-676. doi: 10.1016/j.idc.2020.08.001. Epub 2020 Sep 30.
The evolution of resistance to antimicrobial agents in gram-negatives has challenged the role of the clinical microbiology laboratory to implement new methods for their timely detection. Recent development has enabled the use of novel methods for more rapid pathogen identification, antimicrobial susceptibility testing, and detection of resistance markers. Commonly used methods improve the rapidity of resistance detection from both cultured bacteria and specimens. This review focuses on the commercially available systems available together with their technical performance and possible clinical impact.
革兰氏阴性菌对抗菌药物耐药性的演变，对临床微生物学实验室及时发现耐药性的作用提出了新的挑战。最近的发展使人们能够使用新的方法来更快速地鉴定病原体、进行抗菌药物敏感性测试以及检测耐药标记物。常用的方法可提高从培养细菌和标本中检测耐药性的速度。本文综述了目前市售的各种系统，以及它们的技术性能和可能的临床影响。
