Jaeger M J, Berson P, Kaufman H E, Green W R
Cornea. 1987;6(2):131-9. doi: 10.1097/00003226-198706020-00006.
A 20-year-old man with bilateral keratoconus underwent an epikeratoplasty in the left eye. The postoperative course was uneventful. Five years postepikeratoplasty he developed progressive myopia in the operated eye. A contact lens would not remain centered and the spectacle correction in a trial frame was not tolerated. A successful penetrating keratoplasty was performed six years after the epikeratoplasty procedure. Light and electron microscopic studies of the corneal button showed hypocellularity and irregular distribution of the keratocytes in the lenticule and the accumulation of a periodic acid-Schiff-positive, electron-dense fibrillogranular material at the interface between the lenticule and the recipient Bowman's layer.
一名患有双侧圆锥角膜的20岁男性接受了左眼表层角膜镜片术。术后过程顺利。表层角膜镜片术后5年，他的手术眼出现了进行性近视。隐形眼镜无法保持居中，试镜架中的眼镜矫正也无法耐受。在表层角膜镜片术6年后进行了一次成功的穿透性角膜移植术。对角膜植片进行光镜和电镜研究显示，透镜状组织中角膜细胞减少且分布不规则，在透镜状组织与受者Bowman层之间的界面处有高碘酸-希夫染色阳性、电子致密的纤维颗粒物质积聚。
