Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, Canada.
Rehabilitation Science Institute, University of Toronto, Toronto, Canada.
Dev Neurorehabil. 2021 Apr;24(3):187-198. doi: 10.1080/17518423.2020.1825539. Epub 2020 Oct 4.
A concussion is known as a functional injury affecting brain communication, integration, and processing. There is a need to objectively measure how concussions disrupt brain activation while completing ecologically relevant tasks.The objective of this study was to compare brain activation patterns between concussion and comparison groups (non-concussed youth) during a cognitive-motor single and dual-task paradigm utilizing functional near-infrared spectroscopy (fNIRS) in regions of the frontal-parietal attention network and compared to task performance.Youth with concussion generally exhibited hyperactivation and recruitment of additional brain regions in the dorsal lateral prefrontal (DLPFC), superior (SPC) and inferior parietal cortices (IPC), which are associated with processing, information integration, and response selection. Additionally, hyper- or hypo-activation patterns were associated with slower processing speed on the cognitive task. Our findings corroborate the growing literature suggesting that neural recovery may be delayed compared to the restoration of behavioral performance post-concussion.Concussion, near-infrared spectroscopy, dual-task paradigm, cognitive, motor, brain activation.
脑震荡被认为是一种影响大脑通讯、整合和处理的功能性损伤。需要客观地衡量脑震荡在完成生态相关任务时如何扰乱大脑激活。本研究的目的是比较认知-运动单一和双重任务范式期间，利用功能性近红外光谱（fNIRS）在前额顶叶注意网络区域和与任务表现的比较中，脑震荡和对照组（非脑震荡的青年）之间的大脑激活模式。脑震荡的年轻人通常表现出背外侧前额叶（DLPFC）、上顶叶（SPC）和下顶叶皮质（IPC）的过度激活和额外脑区的募集，这些区域与处理、信息整合和反应选择有关。此外，认知任务的加工速度较慢与过度或不足的激活模式有关。我们的发现证实了越来越多的文献表明，与脑震荡后行为表现的恢复相比，神经恢复可能会延迟。脑震荡、近红外光谱、双重任务范式、认知、运动、大脑激活。
