Department of Epidemiology, West Virginia University, Morgantown, West Virginia; Monongalia County Health Department, Morgantown, West Virginia.
Department of Biostatistics, West Virginia University, Morgantown, West Virginia.
Am J Prev Med. 2020 Nov;59(5):e189-e196. doi: 10.1016/j.amepre.2020.05.022. Epub 2020 Oct 1.
West Virginia leads the nation with the highest rate of acute hepatitis B. From 2013 to 2015, the West Virginia hepatitis B Vaccination Pilot Project distributed more than 10,000 doses of hepatitis B vaccine to at-risk adults through local health department clinics and through outreach to correctional facilities and substance use treatment centers. This study aims to determine which setting type is associated with the greatest likelihood of at-risk adults receiving all 3 or at least 2 doses of hepatitis B vaccine.
Data for this retrospective cohort study were accessed, extracted, and analyzed in 2019 from Pilot Project participant forms initially completed from 2013 to 2015. Odds of receiving all 3 or at least 2 doses were calculated using bivariate, multivariable, and mixed-effects regression models.
Data were available for 1,201 participants. In multivariable logistic regression, participants vaccinated at substance use treatment centers (AOR=1.37, 95% CI=1.01, 1.86) and local health department family planning clinics (AOR=3.74, 95% CI=1.98, 7.06) were more likely to receive the 3-dose series versus those vaccinated at local health department sexually transmitted disease clinics. Participants vaccinated through substance use treatment centers (AOR=1.79, 95% CI=1.31, 2.44), correctional facilities (AOR=3.34, 95% CI=2.09, 5.34), and local health department family planning clinics (AOR=3.97, 95% CI=1.72, 9.16) were more likely to receive at least 2 doses.
Hepatitis B vaccination delivered at local health department family planning clinics, substance use treatment centers, or correctional facilities may increase vaccine dose completion in West Virginia.
西弗吉尼亚州的急性乙型肝炎发病率位居全美之首。在 2013 年至 2015 年期间，西弗吉尼亚州乙型肝炎疫苗接种试点项目通过当地卫生部门诊所，并通过向惩教设施和药物滥用治疗中心提供服务，向高危成年人分发了超过 10000 剂乙型肝炎疫苗。本研究旨在确定哪种接种环境与高危成年人接种全部 3 剂或至少 2 剂乙型肝炎疫苗的可能性最大有关。
本回顾性队列研究的数据于 2019 年从 2013 年至 2015 年期间最初完成的试点项目参与者表格中获取、提取和分析。使用双变量、多变量和混合效应回归模型计算接种全部 3 剂或至少 2 剂的几率。
共有 1201 名参与者的数据可用。在多变量逻辑回归中，与在当地卫生部门性传播疾病诊所接种疫苗的参与者相比，在药物滥用治疗中心（AOR=1.37，95%CI=1.01，1.86）和当地卫生部门计划生育诊所（AOR=3.74，95%CI=1.98，7.06）接种疫苗的参与者更有可能完成 3 剂系列接种。与在当地卫生部门性传播疾病诊所接种疫苗的参与者相比，在药物滥用治疗中心（AOR=1.79，95%CI=1.31，2.44）、惩教设施（AOR=3.34，95%CI=2.09，5.34）和当地卫生部门计划生育诊所（AOR=3.97，95%CI=1.72，9.16）接种疫苗的参与者更有可能接种至少 2 剂。
在当地卫生部门计划生育诊所、药物滥用治疗中心或惩教设施接种乙型肝炎疫苗可能会增加西弗吉尼亚州的疫苗接种剂量完成率。
