Rojulpote Chaitanya, Gonuguntla Karthik, Patil Shivaraj, Bhattaru Abhijit, Bravo Paco E
University of Pennsylvania, Departments of Medicine and Radiology, Philadelphia, United States.
The Wright Center for Graduate Medical Education, Department of Internal Medicine, Scranton, United States.
Colomb Med (Cali). 2020 Jun 30;51(2):e4320. doi: 10.25100/cm.v51i2.4320.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes coronavirus disease 2019 (COVID-19) has resulted in a global health crisis. Prior to the arrival of this viral pandemic, the world was already plagued with a significant burden of cardiovascular disease. With the introduction of the novel virus, the world now faces a double jeapordy. Early reports have suggested an increased risk of death in individuals with underlying cardio-metabolic disorders. The exact effects of COVID-19 on the cardiovascular system are not well determined, however lessons from prior viral epidemics suggest that such infections can trigger acute coronary syndromes, arrhythmias and heart failure via direct and indirect mechanisms. In this article, we aimed to discuss the effects and potential underlying mechanisms of COVID -19 as well as potential implications of treatments targeted against this virus on the cardiovascular system.
导致2019冠状病毒病(COVID-19)的严重急性呼吸综合征冠状病毒2(SARS-CoV-2)已引发全球健康危机。在这场病毒大流行到来之前,全球就已饱受心血管疾病的沉重负担困扰。随着这种新型病毒的出现,世界现在面临双重危险。早期报告表明,患有基础心脏代谢疾病的个体死亡风险增加。然而,COVID-19对心血管系统的确切影响尚未完全明确,不过既往病毒流行的经验表明,此类感染可通过直接和间接机制引发急性冠状动脉综合征、心律失常和心力衰竭。在本文中,我们旨在讨论COVID-19的影响及其潜在机制,以及针对该病毒的治疗方法对心血管系统的潜在影响。