Bortolato Andrea, Simonato Davide, Feltracco Paolo, Munari Marina
Institute of Anesthesia and Intensive Care Medicine, University Hospital of Padova, Padova, Italy.
Institute of Radiology, University Hospital of Padova, Padova, Italy.
J Anaesthesiol Clin Pharmacol. 2020 Apr-Jun;36(2):265-267. doi: 10.4103/joacp.JOACP_251_19. Epub 2020 Jun 15.
Delayed Cerebral Ischemia (DCI) is a major contributor to morbidity and mortality after SAH. Currently the prevention of vasospasm and DCI relies on nimodipine administration and on maintaining an adequate cerebral perfusion pressure. We report a patient with initial DCI after SAH in which stellate ganglion block (SGB) was performed after nimodipine administration. Firstly the procedure was characterized by a iv and intra-arterial nimodipine administration which did not result into a normal perfusion pattern. Therefore a single-shot stellate ganglion block was performed, as suggested in literature. Because of the not sufficient but promising perfusion improvement, we decided to deliver a continuous ganglion block (cSGB) for 5 days. Consequently a further improvement of the cerebral perfusion on CTPerfusion and Real Time Angiographic Perfusion Assessment was registered. In order to treat cerebral vasospasm, SGB is known to be a further valuable treatment, despite its temporary effect. However the continuous use of SGB during initial DCI has never been described before.
迟发性脑缺血(DCI)是蛛网膜下腔出血(SAH)后发病和死亡的主要原因。目前,预防血管痉挛和DCI依赖于尼莫地平给药以及维持足够的脑灌注压。我们报告了一例SAH后最初发生DCI的患者,在给予尼莫地平后进行了星状神经节阻滞(SGB)。首先,该过程的特点是静脉内和动脉内给予尼莫地平,但未导致正常的灌注模式。因此,按照文献建议进行了单次星状神经节阻滞。由于灌注改善不足但有希望,我们决定进行连续5天的神经节阻滞(cSGB)。结果,在CT灌注和实时血管造影灌注评估中记录到脑灌注进一步改善。为了治疗脑血管痉挛,尽管SGB有暂时的效果,但已知它是一种更有价值的治疗方法。然而,此前从未描述过在最初的DCI期间持续使用SGB的情况。