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连续星状神经节阻滞在迟发性脑缺血中的应用:一种传统治疗的可能补充方法?

Continuous stellate ganglion block in delayed cerebral ischemia: A possible supplementary approach to traditional therapy?

作者信息

Bortolato Andrea, Simonato Davide, Feltracco Paolo, Munari Marina

机构信息

Institute of Anesthesia and Intensive Care Medicine, University Hospital of Padova, Padova, Italy.

Institute of Radiology, University Hospital of Padova, Padova, Italy.

出版信息

J Anaesthesiol Clin Pharmacol. 2020 Apr-Jun;36(2):265-267. doi: 10.4103/joacp.JOACP_251_19. Epub 2020 Jun 15.

Abstract

Delayed Cerebral Ischemia (DCI) is a major contributor to morbidity and mortality after SAH. Currently the prevention of vasospasm and DCI relies on nimodipine administration and on maintaining an adequate cerebral perfusion pressure. We report a patient with initial DCI after SAH in which stellate ganglion block (SGB) was performed after nimodipine administration. Firstly the procedure was characterized by a iv and intra-arterial nimodipine administration which did not result into a normal perfusion pattern. Therefore a single-shot stellate ganglion block was performed, as suggested in literature. Because of the not sufficient but promising perfusion improvement, we decided to deliver a continuous ganglion block (cSGB) for 5 days. Consequently a further improvement of the cerebral perfusion on CTPerfusion and Real Time Angiographic Perfusion Assessment was registered. In order to treat cerebral vasospasm, SGB is known to be a further valuable treatment, despite its temporary effect. However the continuous use of SGB during initial DCI has never been described before.

摘要

迟发性脑缺血(DCI)是蛛网膜下腔出血(SAH)后发病和死亡的主要原因。目前,预防血管痉挛和DCI依赖于尼莫地平给药以及维持足够的脑灌注压。我们报告了一例SAH后最初发生DCI的患者,在给予尼莫地平后进行了星状神经节阻滞(SGB)。首先,该过程的特点是静脉内和动脉内给予尼莫地平,但未导致正常的灌注模式。因此,按照文献建议进行了单次星状神经节阻滞。由于灌注改善不足但有希望,我们决定进行连续5天的神经节阻滞(cSGB)。结果,在CT灌注和实时血管造影灌注评估中记录到脑灌注进一步改善。为了治疗脑血管痉挛,尽管SGB有暂时的效果,但已知它是一种更有价值的治疗方法。然而,此前从未描述过在最初的DCI期间持续使用SGB的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbb3/7480307/0f5bb8b60f26/JOACP-36-265-g001.jpg

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