复发性自限性菊池-藤本病的罕见表现
Rare Presentation of Self-Limiting Kikuchi-Fujimoto Disease in Relapsing Nature.
作者信息
Servatyari Karo, Yazdanpanah Hero, Dalugama Chamara
机构信息
Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Lecturer in Medicine, Department of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
出版信息
Case Rep Med. 2020 Sep 21;2020:9785104. doi: 10.1155/2020/9785104. eCollection 2020.
BACKGROUND
Kikuchi-Fujimoto disease (KFD) is a rare, benign, and self-limiting disease that is commonly associated with cervical lymphadenopathy and fever. The disease has a wide spectrum of clinical manifestations, and definitive diagnosis is based on the histological appearance in the excision biopsy of the lymph nodes. Recurrence of KFD is reported rarely. . A 56-year-old Iranian woman with a background history of thrombocytopenia presented with fever, malaise, loss of appetite, and weight loss with cervical lymphadenopathy. The excision biopsy of the cervical lymph nodes confirmed the diagnosis of KFD, and she made a full recovery with improvement of symptoms, regression of cervical lymph nodes, and normalization inflammatory markers. One year after remission, she presented with similar clinico-biochemical profile, and repeat biopsy confirmed KFD.
CONCLUSION
Although the rate of recurrence of the disease is very low, the treating physician should consider the possibility and confirm it histologically.
背景
菊池-藤本病（KFD）是一种罕见的、良性的、自限性疾病，通常与颈部淋巴结病和发热相关。该疾病有广泛的临床表现，确诊基于淋巴结切除活检的组织学表现。KFD复发的报道很少。一名有血小板减少病史的56岁伊朗女性出现发热、不适、食欲不振、体重减轻并伴有颈部淋巴结病。颈部淋巴结切除活检确诊为KFD，她症状改善、颈部淋巴结消退且炎症标志物恢复正常，实现了完全康复。缓解一年后，她出现了类似的临床生化特征，再次活检确诊为KFD。
结论
尽管该疾病的复发率非常低，但治疗医生应考虑复发的可能性并通过组织学检查加以证实。
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