Jin Hwa-Jung, Shin Min-Ho, Myung Eun
Department of Public Health, Graduate School, Chonnam National University Medical School, Gwangju, Korea.
Department of Preventive Medicine, Chonnnam National University Medical School, Gwangju, Korea.
Chonnam Med J. 2020 Sep;56(3):191-195. doi: 10.4068/cmj.2020.56.3.191. Epub 2020 Sep 24.
The purpose of this study was to investigate factors affecting recovery time after sedation for upper gastrointestinal endoscopy. The study population included 1310 patients in the national gastric cancer screening program who received sedation for upper gastrointestinal endoscopy from April 15, 2015 to December 31, 2018. Multivariate regression analysis was performed to identify factors related to recovery time. The mean recovery time after examination was 51.2 minutes (SD=13.3). Patients with a history of hypertension had a recovery time 2.59 minutes shorter than that of patients without hypertension (p=0.006, Bonferroni-corrected p=0.108). Patients with a history of stroke had a recovery time 9.41 minutes longer than that of patients without stroke (p=0.007, Bonferroni-corrected p=0.124). Patients who received 3 mg midazolam had a recovery time 2.99 minutes longer than that of patients received 2 mg (p=0.001, Bonferroni-corrected p=0.010), and patients who received less than 6 cc of propofol had a recovery time 2.90 minutes longer than those that of patients received 7-12 cc of propofol (p<0.001, Bonferroni-corrected p=0.005). These results suggest that receiving high doses of midazolam and having a history of stroke are associated with longer recovery times. Patients meeting these criteria should be managed carefully after sedation for upper gastrointestinal endoscopy.
本研究的目的是调查影响上消化道内镜检查镇静后恢复时间的因素。研究人群包括1310名参加全国胃癌筛查项目的患者，他们在2015年4月15日至2018年12月31日期间接受了上消化道内镜检查镇静。进行多变量回归分析以确定与恢复时间相关的因素。检查后的平均恢复时间为51.2分钟（标准差=13.3）。有高血压病史的患者恢复时间比无高血压病史的患者短2.59分钟（p=0.006，Bonferroni校正p=0.108）。有中风病史的患者恢复时间比无中风病史的患者长9.41分钟（p=0.007，Bonferroni校正p=0.124）。接受3mg咪达唑仑的患者恢复时间比接受2mg咪达唑仑的患者长2.99分钟（p=0.001，Bonferroni校正p=0.010），接受丙泊酚少于6cc的患者恢复时间比接受7-12cc丙泊酚的患者长2.90分钟（p<0.001，Bonferroni校正p=0.005）。这些结果表明，接受高剂量咪达唑仑和有中风病史与较长的恢复时间相关。符合这些标准的患者在上消化道内镜检查镇静后应谨慎管理。
