儿童和成人的免疫与过敏：基于病例的方法。
Immunisation and allergy in children and adults: A case-based approach.
机构信息
MBBS, FRACP, Paediatric Allergist @ Immunologist, Department of Allergy @ Immunology, Women@s and Children@s Hospital, SA; Paediatric Allergist @ Immunologist, Department of Allergy @ Immunology, Flinders Medical Centre, SA.
MBBS, FRACP, PhD, Consultant Paediatrician, Departments of Allergy @ Immunology and General Medicine, The Royal Children@s Hospital, Vic; Group Leader, Population Allergy Research Group, Murdoch Children@s Research Institute, Vic; Honorary Principal Fellow, Department of Paediatrics, The University of Melbourne, Vic.
出版信息
Aust J Gen Pract. 2020 Oct;49(10):637-643. doi: 10.31128/AJGP-07-20-5547.
BACKGROUND
Adverse events following immunisation (AEFIs) are often attributed to vaccine hypersensitivity. However, many of these possible allergic reactions are unlikely to be confirmed as true vaccine allergies but rather coincidental symptoms that may mimic an allergic reaction.
OBJECTIVE
By using case studies, the authors show the variation of presentations of potential hypersensitivity AEFIs. Case studies are used to illustrate a general approach to investigation and management of these reactions.
DISCUSSION
AEFIs are commonly seen in general practice, and it can often be difficult to differentiate between the underlying mechanisms. It is important to be able to identify a potential hypersensitivity reaction so that it can be reported to the appropriate local pharmacovigilance system and patients can be reviewed by immunisation specialists to evaluate, investigate and manage future immunisations where required.
背景
接种疫苗后的不良反应（AEFIs）通常归因于疫苗过敏。然而，其中许多可能的过敏反应不太可能被确认为真正的疫苗过敏，而更可能是巧合的症状，可能类似于过敏反应。
目的
通过使用案例研究，作者展示了潜在过敏反应 AEFIs 的不同表现。案例研究用于说明调查和管理这些反应的一般方法。
讨论
AEFIs 在普通实践中很常见，通常很难区分潜在机制。重要的是能够识别潜在的过敏反应，以便将其报告给适当的当地药物警戒系统，并且可以由免疫专家对患者进行审查，以评估、调查和管理未来需要的免疫接种。
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